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Drug hypersensitivity syndrome
Drug hypersensitivity syndrome (DHS) is an adverse drug reaction commonly associated with the aromatic antiepileptic drugs (AEDs), viz., phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), lamotrigine, primidone, etc. It can also be caused by other drugs, such as sulfonamides, dapsone, minocycline, gold derivatives, cyclosporine, captopril ...
Kumari, Rashmi+2 more
openaire +2 more sources
T-cell mediated drug hypersensitivity reactions may range from mild rash to severe fatal reactions. Among them, drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS), Stevens-Johnson syndrome ...
Chi-Yuan Cheng+5 more
doaj +1 more source
Background: There are several mechanisms to describe allergic drug reactions yet the methods to diagnose them are limited.
Ilan Goldberg+9 more
doaj +1 more source
Exposing Hypersensitivity in Quantum Chaotic Dynamics [PDF]
We demonstrate that the unitary dynamics of a multi-qubit system can display hypersensitivity to initial state perturbation. This contradicts the common belief that the classical approach based on the exponential divergence of initially neighboring trajectories cannot be applied to identify chaos in quantum systems.
arxiv
The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense
Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo+2 more
wiley +1 more source
A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum [PDF]
Artemisinin resistance constitutes a major threat to the continued success of control programs for malaria. With alternative antimalarial drugs not yet available, improving our understanding of how artemisinin-based drugs act and how resistance manifests is essential to enable optimisation of dosing regimens in order to prolong the lifespan of current ...
arxiv +1 more source
Hypersensitivity to Perturbations in the Quantum Baker's Map [PDF]
We analyze a randomly perturbed quantum version of the baker's transformation, a prototype of an area-conserving chaotic map. By numerically simulating the perturbed evolution, we estimate the information needed to follow a perturbed Hilbert-space vector in time. We find that the Landauer erasure cost associated with this information grows very rapidly
arxiv +1 more source
Perspective of delayed Hypersensitivity: A review [PDF]
T cells enter tissues and are activated by antigen-presenting cells to produce cytokines that cause inflammation in the local area. In allergic contact dermatitis, drug eruptions, asthma, and autoimmune disorders, CD8+ T lymphocytes mediate DTH reactions.
Hauwa, Bako+2 more
core +3 more sources
Hypersensitivity and chaos signatures in the quantum baker's maps [PDF]
Classical chaotic systems are distinguished by their sensitive dependence on initial conditions. The absence of this property in quantum systems has lead to a number of proposals for perturbation-based characterizations of quantum chaos, including linear growth of entropy, exponential decay of fidelity, and hypersensitivity to perturbation.
arxiv +1 more source
A Case of Sublingual Ranula That Responded Successfully to Localized Injection Treatment with OK-432 after Healing from Drug Induced Hypersensitivity Syndrome [PDF]
A ranula is a mucus retention cyst or pseudocyst caused by leakage of mucus from the sublingual gland and generally occurs in the oral floor. In addition, drug induced hypersensitivity syndrome (DIHS) is a rare but well-recognized serious adverse effect ...
Akinori Moroi+3 more
core +3 more sources