Tuberculosis treatment-related lichenoid drug eruptions
Tuberculosis is one of the leading causes of death from infectious diseases in adults worldwide. Drug hypersensitivity in tuberculosis is an important problem affecting the treatment process.
Zeynep Yegin Katran+2 more
doaj +1 more source
The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core
Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study [PDF]
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle.
Almeida, C.+5 more
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Immune pathomechanism and classification of drug hypersensitivity
Drug hypersensitivity reactions (DHR) are based on distinct mechanisms and are clinically heterogeneous. Taking into account that also off‐target activities of drugs may lead to stimulations of immune or inflammatory cells, three forms of DHR were ...
W. Pichler
semanticscholar +1 more source
Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
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HLA Association with Drug-Induced Adverse Reactions
Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30 ...
Wen-Lang Fan+6 more
doaj +1 more source
Wound-Dressing-Based Antenna Inkjet-Printed Using Nanosilver Ink for Wireless Medical Monitoring
In this paper, we present a wound-dressing-based antenna fabricated via screen-printed and inkjet-printed technologies. To inkjet print a conductive film on wound dressing, it must be screen-printed, UV-curable-pasted, and hard-baked to provide ...
Chun-Bing Chen+6 more
doaj +1 more source
Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme [PDF]
Observation of adverse drug reactions during drug development can cause closure of the whole programme. However, if association between the genotype and the risk of an adverse event is discovered, then it might suffice to exclude patients of certain ...
Breiman+21 more
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Drug hypersensitivity syndrome
Drug hypersensitivity syndrome (DHS) is an adverse drug reaction commonly associated with the aromatic antiepileptic drugs (AEDs), viz., phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), lamotrigine, primidone, etc. It can also be caused by other drugs, such as sulfonamides, dapsone, minocycline, gold derivatives, cyclosporine, captopril ...
Kumari, Rashmi+2 more
openaire +2 more sources
Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults [PDF]
Background: Drug hypersensitivity is defined as any unfavorable reaction that occurs after the administration of any drug. It may or may not be mediated by the involvement of the immune system.
BEDOLLA BARAJAS, MARTIN+9 more
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