Results 61 to 70 of about 84,588 (320)
Antioxidants, 2021 Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics.
Pedro Ayuso +2 more
doaj +1 more source
Information-theoretic characterization of quantum chaos [PDF]
, 1995 Hypersensitivity to perturbation is a criterion for chaos based on the question of how much information about a perturbing environment is needed to keep the entropy of a Hamiltonian system from increasing. We demonstrate numerically that hypersensitivity to perturbation is present in the following quantum maps: the quantum kicked top, the quantum baker'
arxiv +1 more source
Hypersensitivity vasculitis induced by cefoperazone/sulbactam [PDF]
, 2003 BACKGROUND: Cefoperazone has not been reported to cause vasculitic complications before. Here, we report a case of hypersensitivity vasculitis associated with cefoperazone/sulbactam.
Ali O Katranci +5 more
core +4 more sources
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Housing sulfur: Certain fungi produce diketopiperazine compounds with a transannular sulfur bridge. These so‐called epipolythiodioxopiperzines are toxic by non‐specifically interacting with intracellular proteins and contribute to fungal pathogenicity. Producer strains serve as bio‐pesticides but also question safety of food fermentation.
Eva M. Huber
wiley +1 more source
Drug Selection via Joint Push and Learning to Rank [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics
( Volume: 17, Issue: 1, 01 Jan.-Feb. 2020), 2018 Selecting the right drugs for the right patients is a primary goal of precision medicine. In this manuscript, we consider the problem of cancer drug selection in a learning-to-rank framework. We have formulated the cancer drug selection problem as to accurately predicting 1). the ranking positions of sensitive drugs and 2).
arxiv +1 more source
Advanced Materials, EarlyView.This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle +9 more
wiley +1 more source
Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]
arXiv, 2022 Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv
Acute coronary syndrome in diclofenac sodium-induced type I hypersensitivity reaction : Kounis syndrome [PDF]
, 2007 Drug-induced type I hypersensitivity reactions are frequent. Sometimes, acute coronary syndrome (ACS) can be registered in such patients, which may have a serious impact on the course and management of the allergic reaction.
Gluvic, Zoran M. +5 more
core
The Genetics of Drug Hypersensitivity Reactions [PDF]
Journal of Investigational Allergology and Clinical Immunology, 2016 DHRs are induced by various mechanisms and encompass a heterogeneous set of potentially life-threatening clinical entities. In addition to environmental effects, individual factors play a key role in this intricate puzzle. However, despite commendable efforts in recent years to identify individual predisposing factors, our knowledge of the genetic ...
Cornejo-García, J A +9 more
openaire +4 more sources