Results 71 to 80 of about 84,588 (320)
The aim of this study is to develop a sensor material based on natural quartz combined with La(III) and Ce(III), both detected in Ni‐MH batteries, as well as Eu(III), for reliable qualitative and quantitative analysis of doxycycline over a broad concentration range.
Olha Semeshko+6 more
wiley +1 more source
Carboxymethylcellulose (CMC, carmellose sodium) is an anionic water‐soluble polymer derived from native cellulose that is used as an excipient. Here, we report a case of urticaria caused by the CMC in lidocaine jelly and dimethicone drops. Abstract Excipient allergies are rare and difficult to diagnose.
Eri Hotta+9 more
wiley +1 more source
AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]
Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv
The complexity of drug hypersensitivity reactions [PDF]
Drug hypersensitivity reactions (DHRs) represent a global threat to healthcare systems due to their incidence, with a significant increase over last years.
openaire +6 more sources
Biomarkers of immediate drug hypersensitivity
AbstractImmediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health systems. This problem increases when taking into account that only a small proportion of patients initially labelled as allergic are finally confirmed after an allergological workup.
Cristobalina Mayorga+5 more
openaire +4 more sources
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu+13 more
wiley +1 more source
A remote hypertension management program clinical algorithm
Abstract Introduction Hypertension is the leading risk factor for death, affecting over one billion people worldwide, yet control rates are poor and stagnant. We developed a remote hypertension management program that leverages digitally transmitted home blood pressure (BP) measurements, algorithmic care pathways, and patient–navigator communications ...
Hunter Nichols+3 more
wiley +1 more source
Staphylococcus aureus (S. aureus) infection induces persistent pain via toxins, leading to CGRP release from TRPV1+ nociceptive nerves. CGRP inhibits chemotactic factor release from CX3CR1+ synovial lining macrophages and suppresses their bactericidal activity. This study highlights neuroimmune interactions in chronic septic arthritis and suggests CGRP
Xinyu Fang+19 more
wiley +1 more source
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard+3 more
core +1 more source
Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Severe cutaneous adverse reactions (SCAR) is a T cell-mediated, potentially lethal drug hypersensitivity (DH). Here, the authors identify a carbamazepine-specific TCR common among patients with carbamazepine-induced SCAR that confers SCAR-like pathology ...
Ren-You Pan+17 more
doaj +1 more source