Results 71 to 80 of about 3,996,783 (390)

Efficacy and safety of indigo naturalis oil extract (Lindioil ointment) for the treatment of atopic dermatitis: a randomized, crossover, evaluator-blinded, controlled trial

open access: yesFrontiers in Pharmacology
IntroductionLindioil ointment or its compound formulations are commonly used traditional Chinese medicine practitioners to treat adult eczema or localized dermatitis.
Chin-Yi Yang   +24 more
doaj   +1 more source

Drug hypersensitivity in students from São Paulo, Brazil

open access: yesClinics, 2010
BACKGROUND: Drug hypersensitivity is responsible for substantial mortality and morbidity, and increased health costs. However, epidemiological data on drug hypersensitivity in general or specific populations are scarce.
Luis Felipe Chiaverini Ensina   +5 more
doaj   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

The complexity of drug hypersensitivity reactions [PDF]

open access: yesAllergy, 2020
Drug hypersensitivity reactions (DHRs) represent a global threat to healthcare systems due to their incidence, with a significant increase over last years.
openaire   +6 more sources

The Genetics of Drug Hypersensitivity Reactions [PDF]

open access: yesJournal of Investigational Allergology and Clinical Immunology, 2016
DHRs are induced by various mechanisms and encompass a heterogeneous set of potentially life-threatening clinical entities. In addition to environmental effects, individual factors play a key role in this intricate puzzle. However, despite commendable efforts in recent years to identify individual predisposing factors, our knowledge of the genetic ...
Cornejo-García, J A   +9 more
openaire   +4 more sources

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

open access: yesAdvanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang   +12 more
wiley   +1 more source

Enhanced c-Fos expression in the central amygdala correlates with increased thigmotaxis in rats with peripheral nerve injury [PDF]

open access: yes, 2015
Pain is associated with affective, cognitive and sensory dysfunction. Animal models can be used to observe ethologically relevant behaviours such as thigmotaxis, giving insight into how ongoing sensory abnormalities influence natural rodent behaviours ...
Rice, ASC
core   +1 more source

Recent developments and highlights in drug hypersensitivity

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2019
Drug hypersensitivity reactions (DHRs) are nowadays the third cause of allergy after rhinitis and asthma with a significant increase in prevalence in both adults and paediatric population with new drugs included as culprit.
C. Mayorga   +4 more
semanticscholar   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

open access: yesAdvanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle   +9 more
wiley   +1 more source

Cosmetic Talc-Related Pulmonary Granulomatosis. [PDF]

open access: yes, 2017
Inhalation of cosmetic talc can lead to pulmonary foreign-body granulomatosis, though fewer than 10 cases of inhaled cosmetic talc-related pulmonary granulomatosis have been reported in adults.
Adams, Jason Y   +3 more
core   +1 more source

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