Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Sulfone Syndrome: A Unique Delayed Type of Drug Hypersensitivity from Dapsone
Journal of Health Science and Medical Research (JHSMR)Nowadays, dapsone is more commonly used in some dermatologic and inflammatory conditions other than leprosy. Even though it has excellent therapeutic efficacy, its side effects are of common concern. Although immune mediated drug hypersensitivity is less
Metus Thungthienthong +2 more
doaj +1 more source
Case Report: DRESS Syndrome Induced by Two Antituberculosis Drugs in an 8-Year-Old Girl
Frontiers in Pediatrics, 2022 DRESS syndrome is defined as drug-induced hypersensitivity syndrome with rash, eosinophilia, and systemic symptoms. This syndrome is mostly associated with anticonvulsants, antibacterial and anti-inflammatory drugs.
Vaidotas Urbonas +4 more
doaj +1 more source
AGING MEDICINE, EarlyView.Geriatric asthmatics exhibit more comorbidities, poorer lung function, higher neutrophil ratios, and elevated CRP levels. ABSTRACT Objective The research analyzed the clinical characteristics of geriatric and nongeriatric asthma cases, aiming to provide new insights into the diagnosis and management of geriatric asthma for clinicians.
Mengxia Gu +4 more
wiley +1 more source
Journal of Medical Case ReportsBackground Vancomycin-induced delayed hypersensitivity reactions are rare and typically accompanied by systemic symptoms such as fever, eosinophilia, and organ dysfunction, known as drug reaction with eosinophilia and systemic symptoms syndrome. However,
Chien-Hung Chou +3 more
doaj +1 more source
The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]
, 2020 A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core
Increased mortality in hematological malignancy patients with acute respiratory failure from undetermined etiology : a Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologique (Grrr-OH) study [PDF]
, 2016 Background: Acute respiratory failure (ARF) is the most frequent complication in patients with hematological malignancies and is associated with high morbidity and mortality.
Azoulay, Elie +19 more
core +2 more sources
Work‐Related Asthma From Exposure to Cardboard and Paper Products
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background We assess the contribution of cardboard dust exposure to the development of work‐related asthma (WRA). Prior studies on paper‐dust‐related breathing problems have focused on exposures in the paper milling and pulp industries. There have been no reports of asthma linked to workplace exposure to cardboard dust.
Mason E. Glanville +2 more
wiley +1 more source
SÍNDROME POR REACCIÓN A DROGAS CON EOSINOFILIA Y SÍNTOMAS SISTÉMICOS (DRESS)
Revistas Argentina de Medicina, 2019 El síndrome DRESS (por sus siglas en inglés de drug rash with eosinophilia and systemic symptoms) es una reacción grave de hipersensibilidad a diferentes fármacos, entre los que podemos mencionar los anticonvulsivos, sulfonamidas y algunos fármacos ...
Hugo Milione +3 more
doaj +2 more sources
1436 Lesional skin histology in drug-induced hypersensitivity syndrome: A single center 10-year experience of 37 patients [PDF]
, 2023 E. Borzova +4 more
openalex +1 more source