Results 121 to 130 of about 7,440,138 (398)

Política farmacéutica saludable Healthy pharmaceutical policy

Salud Pública de México, 2008
Hoy en día, la industria farmacéutica se encuentra en una transición profunda. La globalización y el avance tecnológico representan las principales presiones de cambio para un mercado mundial de medicamentos donde a este tipo de industria le resulta cada
Eduardo González Pier
doaj  

Contribuições do modelo Fatores Críticos de Sucesso para análise da gestão de Parcerias para o Desenvolvimento Produtivo de um laboratório oficial

Cadernos de Saúde Pública
Resumo: A Parceria para o Desenvolvimento Produtivo (PDP) é uma das medidas usada pelo Estado brasileiro para incentivar a política de inovação, ampliar o acesso da população a medicamentos estratégicos e reduzir a dependência tecnológica do país, por ...
Daniela Rangel Affonso Fernandes, Sheyla Maria Lemos Lima, Roberto Pierre Chagnon   +2 more
doaj   +1 more source

Opportunities for Improving the Drug Development Process: Results from a Survey of Industry and the FDA [PDF]

In the United States, the Food and Drug Administration (FDA) agency is responsible for regulating the safety and efficacy of biopharmaceutical drug products. Furthermore, the FDA is tasked with speeding new medical innovations to market.
Adrian H. B. Gottschalk, Ernst R. Berndt, Matthew W. Strobeck   +2 more
core  

HyperLoom: A platform for defining and executing scientific pipelines in distributed environments [PDF]

, 2018
Real-world scientific applications often encompass end-to-end data processing pipelines composed of a large number of interconnected computational tasks of various granularity.
Ashby, Thomas J., Böhm, Stanislav, Chupakhin, Vladimir, Cima, Vojtěch, Dvorský, Jiří, Janurová, Kateřina, Martinovič, Jan, Vander Aa, Tom   +7 more
core   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Image quality comparisons of coil setups in 3T MRI for brain and head and neck radiotherapy simulations

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose MRI is increasingly used for brain and head and neck radiotherapy treatment planning due to its superior soft tissue contrast. Flexible array coils can be arranged to encompass treatment immobilization devices, which do not fit in diagnostic head/neck coils. Selecting a flexible coil arrangement to replace a diagnostic coil should rely
Evangelia Kaza, Jeffrey P. Guenette, Christian V. Guthier, Steven Hatch, Alexander Marques, Lisa Singer, Jonathan D. Schoenfeld   +6 more
wiley   +1 more source

Automatic Detection and Classification of Waste Consumer Medications for Proper Management and Disposal [PDF]

arXiv, 2020
Every year, millions of pounds of medicines remain unused in the U.S. and are subject to an in-home disposal, i.e., kept in medicine cabinets, flushed in toilet or thrown in regular trash. In-home disposal, however, can negatively impact the environment and public health.
arxiv  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal, Dario B. Rodrigues, Weiguang Yao, Jason K. Molitoris, Matthew E. Witek, Shifeng Chen   +5 more
wiley   +1 more source

Advancements and future prospective of DNA barcodes in the herbal drug industry. [PDF]

Front Pharmacol, 2022
Mahima K, Sunil Kumar KN, Rakhesh KV, Rajeswaran PS, Sharma A, Sathishkumar R.   +5 more
europepmc   +1 more source