Results 21 to 30 of about 285,764 (313)
Potential therapies against SARS-CoV-2 virus evaluated in large-scale clinical trials [PDF]
COVID-19 is a viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 infection in humans manifests as mild symptoms to severe respiratory failure.
Alin-Viorel Focsa +4 more
doaj +1 more source
Midlands awareness group concerned by impact of virus on the drug industry. [PDF]
Lockdown restrictions are impacting the ability of drug dealers to reach their market.
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Responsibilities of the Marketing Authorisation Holders in Respect of GMP Compliance (Review)
Introduction. The article is focused on differences in quality assurance-related obligations and responsibilities between Marketing Authorisation Holders (MAHs) and manufacturing authorisation holder (manufacturers) in pharmaceutical industry. In case of
A. P. Meshkovskiy +7 more
doaj +1 more source
Chiral Analysis of the Key Intermediates of Tenofovir Alafenamide Fumarate
(R)-Tenofovir phenyl ester ((R)-1) and (R)-tenofovir diphenyl ester ((R)-2) are key intermediates for the practical synthesis of tenofovir alafenamide fumarate, which is a mainstay antiretroviral for the treatment of chronic hepatitis B and HIV-1 ...
Man Li, Ting Zhou, Qing-Wen Zhang
doaj +1 more source
Synthesis and Antitumor Activity of (3-Hydroxyacrylato-O,O′) Diammineplatinum(II)
As an indispensable part of cancer chemotherapy, platinum drugs still play an important role in cancer treatment. In this study, two platinum(II) complexes with Michael acceptor 3-hydroxyacrylic acid as the leaving group were synthesized from cis ...
Yong-Zhi Shu +6 more
doaj +1 more source
Background The availability of a reliable tumor target for advanced colorectal cancer (CRC) therapeutic approaches is critical since current treatments are limited.
Ting-Yi Sung +9 more
doaj +1 more source
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa +7 more
wiley +1 more source
Regulations Governing Drug Trials in Turkey [PDF]
The ethical issues involved in drug trials using human subjects have become a challenge to the investigators involved. The needs of the drug industry and the increase in the number of such trials have added to these problems.
Aydin, Erdem
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OBJECTIVE: The World Trade Organization's Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement establishes minimum standards for intellectual property rights, including patent protection for pharmaceuticals; therefore, it may make it ...
Maria Auxiliadora Oliveira +3 more
doaj +1 more source
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source

