Results 21 to 30 of about 285,764 (313)

Potential therapies against SARS-CoV-2 virus evaluated in large-scale clinical trials [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice, 2022
COVID-19 is a viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 infection in humans manifests as mild symptoms to severe respiratory failure.
Alin-Viorel Focsa   +4 more
doaj   +1 more source

Midlands awareness group concerned by impact of virus on the drug industry. [PDF]

open access: yes, 2020
Lockdown restrictions are impacting the ability of drug dealers to reach their market.

core  

Responsibilities of the Marketing Authorisation Holders in Respect of GMP Compliance (Review)

open access: yesРазработка и регистрация лекарственных средств, 2020
Introduction. The article is focused on differences in quality assurance-related obligations and responsibilities between Marketing Authorisation Holders (MAHs) and manufacturing authorisation holder (manufacturers) in pharmaceutical industry. In case of
A. P. Meshkovskiy   +7 more
doaj   +1 more source

Chiral Analysis of the Key Intermediates of Tenofovir Alafenamide Fumarate

open access: yesPharmaceutical Fronts, 2023
(R)-Tenofovir phenyl ester ((R)-1) and (R)-tenofovir diphenyl ester ((R)-2) are key intermediates for the practical synthesis of tenofovir alafenamide fumarate, which is a mainstay antiretroviral for the treatment of chronic hepatitis B and HIV-1 ...
Man Li, Ting Zhou, Qing-Wen Zhang
doaj   +1 more source

Synthesis and Antitumor Activity of (3-Hydroxyacrylato-O,O′) Diammineplatinum(II)

open access: yesPharmaceutical Fronts, 2021
As an indispensable part of cancer chemotherapy, platinum drugs still play an important role in cancer treatment. In this study, two platinum(II) complexes with Michael acceptor 3-hydroxyacrylic acid as the leaving group were synthesized from cis ...
Yong-Zhi Shu   +6 more
doaj   +1 more source

EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

open access: yesCell & Bioscience, 2021
Background The availability of a reliable tumor target for advanced colorectal cancer (CRC) therapeutic approaches is critical since current treatments are limited.
Ting-Yi Sung   +9 more
doaj   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa   +7 more
wiley   +1 more source

Regulations Governing Drug Trials in Turkey [PDF]

open access: yes, 2003
The ethical issues involved in drug trials using human subjects have become a challenge to the investigators involved. The needs of the drug industry and the increase in the number of such trials have added to these problems.
Aydin, Erdem
core  

Has the implementation of the TRIPS Agreement in Latin America and the Caribbean produced intellectual property legislation that favours public health?

open access: yesBulletin of the World Health Organization
OBJECTIVE: The World Trade Organization's Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement establishes minimum standards for intellectual property rights, including patent protection for pharmaceuticals; therefore, it may make it ...
Maria Auxiliadora Oliveira   +3 more
doaj   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

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