Results 31 to 40 of about 285,764 (313)

Evaluation Of The Performance Of Companies Operating In The Pharmaceutical Sector For Reverse Logistics Applications With TOPSIS and MOORA Methods

Journal of Transportation and Logistics, 2019
Reverse logistics activities, which are the process of taking products back to the supply chain point for disposal and recycling are quite expensive and complex.
Batuhan Kocaoğlu, Aykut Küçük
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Marketing research of the national antiarrhythmic drugs market

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The purpose – marketing research of the national antiarrhythmic drugs market.Materials and methods. The State Register of Medicinal Products of Ukraine and Compendium-2019 were used as the research materials. Methods of system, marketing, statistical and
T. P. Zarichna, T. S. Raikova, T. S. Brytanova, Assani Doshi Rainna   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Seattle Drug Store prescription, circa 1880 [PDF]

, 1880
Moses Rideout Maddocks (1833-1919) arrived in Washington Territory in 1858, where he worked as a logger and was elected to the state legislature (he later served as Seattle's fourth mayor).
Seattle Drug Store
core  

Evaluation of Biological Mechanisms of Quanduzhong Capsule for Treating Osteoporosis by Integrating Untargeted Metabolomics and Network Pharmacology

Pharmaceutical Fronts, 2023
Osteoporosis (OP) is a metabolic disease characterized by bone formation and resorption disturbances. Quanduzhong Capsule (QDZC) is a common treatment for OP in China; however, the effective components and metabolites of the drug after oral ...
Fang-Fang Yu, Le-Yi Huang, Man-Man Li, Shi-Wen Cui, Jie Yuan, Xiao-Feng Li, Tong Wu   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Financing Drug Research: What are the Issues? [PDF]

, 2008
The current system of patent financing for prescription drug research leads to large and growing inefficiencies. In addition, patent rents create perverse incentives that can lead to both bad health outcomes and the slowing of the research process.
Baker, Dean, Dean Baker
core   +1 more source

Farmacologia no século XX: a ciência dos medicamentos a partir da análise do livro de Goodman e Gilman Pharmacology in the twentieth century: the science of drugs through the analysis of Goodman and Gilman's textbook

História, Ciências, Saúde: Manguinhos, 2013
Analisa a apresentação da farmacologia como ciência a partir do livro-texto de Louis Goodman e Alfred Gilman reeditado e reimpresso inúmeras vezes entre 1941 e 2006. Nas primeiras edições, a farmacologia é caracterizada
Silvia Cardoso Bittencourt, Sandra Caponi, Sônia Maluf   +2 more
doaj  

A new era for African health systems: Market shaping and the African Continental Free Trade Area (AfCFTA)

Public Health Challenges
The COVID‐19 pandemic has forced a reflection on the origins of supplies in African healthcare market and underscored the need for an increase in local manufacturing of medical supplies. Several African countries’ health markets have been heavily reliant
Jonta Kamara, Ukeme Essien, Alain Labrique   +2 more
doaj   +1 more source