Results 31 to 40 of about 948,070 (312)
Cell & Bioscience, 2021 Background The availability of a reliable tumor target for advanced colorectal cancer (CRC) therapeutic approaches is critical since current treatments are limited.
Ting-Yi Sung +9 more
doaj +1 more source
Pathways Across the Valley of Death: Novel Intellectual Property Strategies for Accelerated Drug Discovery [PDF]
, 2008 Drug discovery is stagnating. Government agencies, industry analysts, and industry scientists have all noted that, despite significant increases in pharmaceutical R&D funding, the production of fundamentally new drugs - particularly drugs that work on ...
Crossman, Colin +3 more
core +1 more source
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Bulletin of the World Health OrganizationOBJECTIVE: The World Trade Organization's Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement establishes minimum standards for intellectual property rights, including patent protection for pharmaceuticals; therefore, it may make it ...
Maria Auxiliadora Oliveira +3 more
doaj +1 more source
Journal of Transportation and Logistics, 2019 Reverse logistics activities, which are the process of taking products back to the supply chain point for disposal and recycling are quite expensive and complex.
Batuhan Kocaoğlu, Aykut Küçük
doaj +1 more source
WORKPLACE SUBSTANCE USE, THE RISK OF OCCUPATIONAL INJURY, AND TESTING [PDF]
, 2005 Over the past 20 years, the "workplace substance abuse prevention industry" has grown enormously in size and has become more sophisticated in its marketing approach. Drug testing alone has become a $6 billion industry.
Zimbardi, Guy
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Pharmaceutical Fronts, 2023 Osteoporosis (OP) is a metabolic disease characterized by bone formation and resorption disturbances. Quanduzhong Capsule (QDZC) is a common treatment for OP in China; however, the effective components and metabolites of the drug after oral ...
Fang-Fang Yu +6 more
doaj +1 more source
Willful Misconduct: How Bill Frist and the Drug Lobby Covertly Bagged a Liability Shield [PDF]
, 2006 Drug industry lobbyists conspired with the White House and Senate Majority Leader Bill Frist (R-Tenn.) last year to craft a sweeping liability provision that shields the industry from lawsuits over products used to treat pandemic illnesses, even in cases
John O'Donnell
core
HyperLoom: A platform for defining and executing scientific pipelines in distributed environments [PDF]
, 2018 Real-world scientific applications often encompass end-to-end data processing pipelines composed of a large number of interconnected computational tasks of various granularity.
Ashby, Thomas J. +7 more
core +1 more source