Results 31 to 40 of about 4,952,093 (307)
Pharmaceutical Fronts, 2021 A series of mono- or bis-quaternary ammonium salts derived from cinchonidine or quinine was synthesized and screened as potent phase-transfer catalysts for the reaction of aza-Michael cyclization, the key step in the synthesis of letermovir.
Liang Chen +7 more
doaj +1 more source
Potential therapies against SARS-CoV-2 virus evaluated in large-scale clinical trials [PDF]
Romanian Journal of Pharmaceutical Practice, 2022 COVID-19 is a viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 infection in humans manifests as mild symptoms to severe respiratory failure.
Alin-Viorel Focsa +4 more
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Responsibilities of the Marketing Authorisation Holders in Respect of GMP Compliance (Review)
Разработка и регистрация лекарственных средств, 2020 Introduction. The article is focused on differences in quality assurance-related obligations and responsibilities between Marketing Authorisation Holders (MAHs) and manufacturing authorisation holder (manufacturers) in pharmaceutical industry. In case of
A. P. Meshkovskiy +7 more
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Chiral Analysis of the Key Intermediates of Tenofovir Alafenamide Fumarate
Pharmaceutical Fronts, 2023 (R)-Tenofovir phenyl ester ((R)-1) and (R)-tenofovir diphenyl ester ((R)-2) are key intermediates for the practical synthesis of tenofovir alafenamide fumarate, which is a mainstay antiretroviral for the treatment of chronic hepatitis B and HIV-1 ...
Man Li, Ting Zhou, Qing-Wen Zhang
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Synthesis and Antitumor Activity of (3-Hydroxyacrylato-O,O′) Diammineplatinum(II)
Pharmaceutical Fronts, 2021 As an indispensable part of cancer chemotherapy, platinum drugs still play an important role in cancer treatment. In this study, two platinum(II) complexes with Michael acceptor 3-hydroxyacrylic acid as the leaving group were synthesized from cis ...
Yong-Zhi Shu +6 more
doaj +1 more source
Evaluation of the Peer Support Program (Student Drug Prevention) 1986-1987
, 2019 The Peer Support program is a school based program funded by the National Campaign Against Drug Abuse (NCADA) as a drug prevention strategy. Prior to the existence of the NCADA the program was funded through the NSW Drug and Alcohol Authority.
Directorate of the Drug Offensive
core +1 more source
Cell & Bioscience, 2021 Background The availability of a reliable tumor target for advanced colorectal cancer (CRC) therapeutic approaches is critical since current treatments are limited.
Ting-Yi Sung +9 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]
, 2014 This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core
Bulletin of the World Health OrganizationOBJECTIVE: The World Trade Organization's Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement establishes minimum standards for intellectual property rights, including patent protection for pharmaceuticals; therefore, it may make it ...
Maria Auxiliadora Oliveira +3 more
doaj +1 more source