Results 81 to 90 of about 3,913,962 (299)

The Five Factor Model of personality and evaluation of drug consumption risk

, 2017
The problem of evaluating an individual's risk of drug consumption and misuse is highly important. An online survey methodology was employed to collect data including Big Five personality traits (NEO-FFI-R), impulsivity (BIS-11), sensation seeking (ImpSS)
A. Terracciano, A.N. Gorban, A.N. Gorban, A.N. Kopstein, C.A. Ventura, D.N. Gujarati, D.W. Hosmer Jr, D.W. Scott, E.M. Mirkes, E.M. Mirkes, F. Bulut, G. Biau, G.P. McCabe, H.F. Kaiser, I.D. Dinov, J. Hoare, J.R. Quinlan, K. Pearson, K.L. Clarkson, L. Guttman, M. Linting, M. Zuckerman, M.J. Cleveland, M.S. Stanford, P.T. Costa, Q. Li, R. Beaglehole, R.A. Fisher, R.R. McCrae, S. Arlot, S. Russell, S. Valeroa, S.Y. Lee, T. Bogg, T. Hastie, T. Hastie, V. Egan, Y. Benjamini, Y. Koren   +38 more
core   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Findings from the DUMA program: internet access, and frequency and nature of use among police detainees [PDF]

Examining access to and the extent of engagement with the Internet in illicit drug-using populations may provide an indication of the extent to which the online illicit drug market is usurping the physical illicit drug market, according to this report ...
Eileen Patterson, Susan Goldsmid
core  

Characteristics of drug users who do or do not have care of their children

, 2004
Aims - To compare the relative frequency of eight indicators of problem drug use and potentially adverse social circumstances in drug using parents and non-parents and to explore whether a profile based on these characteristics differs according to ...
Advisory Council on the Misuse of Drugs, Barnard, Bauman, Bays, Donmall, Famularo, Gawin, Hogan, Jeremy, Johnson, Johnson, Kandel, Kaplan-Sanoff, Kelley, Kolar, Pilowsky, Rubin, Suchman, Wilens   +18 more
core   +1 more source

Benchmarking network propagation methods for disease gene identification [PDF]

, 2019
In-silico identification of potential target genes for disease is an essential aspect of drug target discovery. Recent studies suggest that successful targets can be found through by leveraging genetic, genomic and protein interaction information.
Barrett, Steven J., Dessailly, Benoit H., Gutteridge, Alex, Perera Lluna, Alexandre, Picart Armada, Sergio, Willé, David R.   +5 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Prenatal Drug Use and the Production of Infant Health [PDF]

We estimate the effect of illicit drug use during pregnancy on low birth weight. We use data from a national longitudinal study of urban parents that includes post-partum interviews with mothers, hospital medical record data on the mother and newborn ...
Dhaval Dave, Hope Corman, Kelly Noonan, Nancy E. Reichman   +3 more
core  

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Navigating Recent Changes in Dosing Information: Dynamics of FDA‐Approved Monoclonal Antibodies in Post‐Marketing Realities

Clinical and Translational Science
Monoclonal antibodies (mAbs) are critical components in the therapeutic landscape, but their dosing strategies often evolve post‐approval as new data emerge.
Nai Lee, Su‐jin Rhee, Seong Min Koo, So Won Kim, Gyo Eun Lee, Yoon A Yie, Yun Kim   +6 more
doaj   +1 more source