Results 31 to 40 of about 2,189,430 (305)

Understanding Pharmacokinetic-Drug Interactions With Drugs Approved by the US Food and Drug Administration in 2024 to Better Manage the Risk of Drug Interactions With Concomitant Medications: A Review of Clinical Data From New Drug Applications

open access: yesCurrent Therapeutic Research
Objective: This analysis aimed to provide a mechanistic understanding and an evaluation of the clinical relevance of pharmacokinetic drug-drug interactions (DDIs) associated with drugs approved by the Food and Drug Administration in 2024.
Jingjing Yu, MD, PhD   +4 more
doaj   +1 more source

Report on Provider-Client Interaction From 68 Methadone Maintenance Clinics in China. [PDF]

open access: yes, 2016
Provider-client interaction is an integral of clinical practice and central to the delivery of high-quality medical care. This article examines factors related to the provider-client interaction in the context of methadone maintenance treatment (MMT ...
Cao, Xiaobin   +5 more
core   +1 more source

Drug-drug interaction

open access: yesJornal Brasileiro de Nefrologia, 2014
A doenca renal cronica (DRC), considerada a grande epidemia deste milenio, tem prevalencia media de 11% nos paises desenvolvidos. Infelizmente, no Brasil ainda nao dispomos de dados definitivos sobre a prevalencia da DRC, contudo, estudo realizado em amostra de 24.248 individuos adultos, utilizando o criterio de DRC baseado em duas determinacoes da ...
openaire   +2 more sources

Pharmacodynamic Drug–Drug Interactions [PDF]

open access: yesClinical Pharmacology & Therapeutics, 2019
Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms are frequently misused.
Jin, Niu   +2 more
openaire   +2 more sources

Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]

open access: yes, 2020
For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad   +4 more
core   +1 more source

Metabolite Measurement in Index Substrate Drug Interaction Studies: A Review of the Literature and Recent New Drug Application Reviews

open access: yesMetabolites
Background/Objectives: Index substrates are used to understand the processes involved in pharmacokinetic (PK) drug–drug interactions (DDIs). The aim of this analysis is to review metabolite measurement in clinical DDI studies, focusing on index ...
Jingjing Yu   +4 more
doaj   +1 more source

Potential Drug - Drug Interactions among Medications Prescribed to Hypertensive Patients [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Context: Drug-drug interactions(DDIs) are significant but avoidable causes of iatrogenic morbidity and hospital admission. Aim: To detect potential drug-drug interactions among medications received by hypertensive patients.
Nitin Kothari, Barna Ganguly
doaj   +1 more source

Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters [PDF]

open access: yes, 2019
OBJECTIVES: The secondary use of medical data contained in electronic medical records, such as hospital discharge letters, is a valuable resource for the improvement of clinical care (e.g. in terms of medication safety) or for research purposes. However,
Demuth, Ilja   +4 more
core   +1 more source

Announcing the 2015 Viruses Young Investigator Prize and Graduate Student/Postdoctoral Fellow Travel Awards

open access: yesViruses, 2015
With the goal of recognizing outstanding contributions to the field of virology by early-career investigators, last year Viruses accepted nominations for a 2015 Young Investigator Prize in Virology. The target age was set at 40 and under.
Eric O. Freed
doaj   +1 more source

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger   +4 more
wiley   +1 more source

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