Results 41 to 50 of about 1,220,078 (316)

Warfarin - Sulfamethoxazole-trimethoprim - contextualized potential drug-drug interaction clinical algorithm

open access: yes, 2018
An algorithm developed for research purposes that summarizes the potential drug-drug interaction between Warfarin - Sulfamethoxazole-trimethoprim. The information is not advice, and should not be treated as such.
Contributors to the A Minimum Representation of Potential Drug-Drug Interaction Knowledge and Evidence - Technical and User-centered Foundation Specification
core   +1 more source

Drug metabolism and liver disease: a drug–gene–environment interaction [PDF]

open access: yes, 2017
Despite the central role of the liver in drug metabolism, surprisingly there is lack of certainty in anticipating the extent of modification of the clearance of a given drug in a given patient.
Khoueiry-Zgheib, Nathalie   +1 more
core   +1 more source

Tamoxifen-Paroxetine - contextualized potential drug-drug interaction clinical algorithm

open access: yes, 2018
An algorithm developed for research purposes that summarizes the potential drug-drug interaction between tamoxifen and paroxetine. The information is not advice, and should not be treated as such.
Contributors to the A Minimum Representation of Potential Drug-Drug Interaction Knowledge and Evidence - Technical and User-centered Foundation Specification
core   +1 more source

Drug interaction and chronic obstructive respiratory disorders

open access: yes, 2021
: Chronic obstructive respiratory disorders uncontrolled by monotherapy should be given combinations of drugs that act by distinct mechanisms of action. The rationale for combining different classes of drugs should be to elicit a synergistic interaction,
Zerillo, Bartolomeo   +4 more
core   +2 more sources

Metabolite Measurement in Index Substrate Drug Interaction Studies: A Review of the Literature and Recent New Drug Application Reviews

open access: yesMetabolites
Background/Objectives: Index substrates are used to understand the processes involved in pharmacokinetic (PK) drug–drug interactions (DDIs). The aim of this analysis is to review metabolite measurement in clinical DDI studies, focusing on index ...
Jingjing Yu   +4 more
doaj   +1 more source

Amiodarone - Simvastatin - contextualized potential drug-drug interaction clinical algorithm

open access: yes, 2018
An algorithm developed for research purposes that summarizes the potential drug-drug interaction between amiodarone and simvastatin. The information is not advice, and should not be treated as such.
Contributors to the A Minimum Representation of Potential Drug-Drug Interaction Knowledge and Evidence - Technical and User-centered Foundation Specification
core   +1 more source

NOACs: drug–drug interactions [PDF]

open access: yesCanadian Medical Association Journal, 2016
We commend Fralick and colleagues for their article on drug interactions with rivaroxaban.[1][1] All novel oral anticoagulants (NOACs) were introduced as at least noninferior (in some cases superior) to warfarin.
Bartosz, Hudzik   +2 more
openaire   +2 more sources

Allo-network drugs: Extension of the allosteric drug concept to protein-protein interaction and signaling networks [PDF]

open access: yes, 2013
Allosteric drugs are usually more specific and have fewer side effects than orthosteric drugs targeting the same protein. Here, we overview the current knowledge on allosteric signal transmission from the network point of view, and show that most ...
Csermely, Péter   +3 more
core   +1 more source

Announcing the 2015 Viruses Young Investigator Prize and Graduate Student/Postdoctoral Fellow Travel Awards

open access: yesViruses, 2015
With the goal of recognizing outstanding contributions to the field of virology by early-career investigators, last year Viruses accepted nominations for a 2015 Young Investigator Prize in Virology. The target age was set at 40 and under.
Eric O. Freed
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

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