Results 61 to 70 of about 6,568,172 (215)
Clinical and Translational Science, 2023 Smoking drug interaction studies represent a common approach for the clinical investigation of CYP1A2 induction. Despite this important role, they remain an “orphan topic” in the existing regulatory framework of drug interaction studies, and important ...
Robert Hermann +3 more
doaj +1 more source
Drug interaction and chronic obstructive respiratory disorders
, 2021 : Chronic obstructive respiratory disorders uncontrolled by monotherapy should be given combinations of drugs that act by distinct mechanisms of action. The rationale for combining different classes of drugs should be to elicit a synergistic interaction,
Zerillo, Bartolomeo +4 more
core +1 more source
Drug-Drug Interaction of Antifungal Drugs
YAKUGAKU ZASSHI, 2005 This article reviews the in vitro metabolic and the in vivo pharmacokinetic drug-drug interactions with antifungal drugs, including fluconazole, itraconazole, micafungin, miconazole, and voriconazole. In the in vitro interaction studies, the effects of antifungal drugs on specific activities of cytochrome P450s (CYPs), including CYP1A2, CYP2C9, CYP2C19,
Toshiro, Niwa +2 more
openaire +3 more sources
Journal of Functional FoodsWe aimed to investigate the effects of a probiotic mixture comprising Lactiplantibacillus plantarum, Bifidobacterium breve, Bifidobacterium animal subsp.
So Yeon Jeon +9 more
doaj +1 more source
Drug-gene interaction networks.
, 2023 Type 2 diabetes (T2D) is one of the major metabolic disorders in humans caused by hyperglycemia and insulin resistance syndrome. Although significant genetic effects on T2D pathogenesis are experimentally proved, the molecular mechanism of T2D in South ...
Md. Golam Rabby (13514311) +6 more
core +1 more source
, 2016 The UK Medicines and Healthcare products Regulatory Agency received a Coroner’s report that raised concerns about a suspected drug interaction between citalopram and cocaine after the death of a man due to subarachnoid haemorrhage.
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Chemically Interpretable Graph Interaction Network for Prediction of Pharmacokinetic Properties of Drug-like Molecules [PDF]
, 2019 Solubility of drug molecules is related to pharmacokinetic properties such as absorption and distribution, which affects the amount of drug that is available in the body for its action.
U. Deva, Priyakumar +3 more
core +1 more source
Drug-interaction annotations over a large set of drug product labels
, 2018 <p>Drug interaction annotations over a large set of drug product labels. These annotations were done as part of the National Library of Medicine funded research project "Addressing gaps in clinically useful evidence on drug-drug interactions ...
Richard D. Boyce (8214180) +1 more
core +1 more source
PXR as a mediator of herb–drug interaction
, 2017 Medicinal herbs have been a part of human medicine for thousands of years. The herb–drug interaction is an extension of drug–drug interaction, in which the consumptions of herbs cause alterations in the metabolism of drugs the patients happen to take at ...
Xiudong Guan +11 more
core +1 more source
Automatic Drug-Drug Interaction Detection: A Machine Learning Approach With Maximal Frequent Sequence Extraction [PDF]
, 2011 [EN] A Drug-Drug Interaction (DDI) occurs when the effects of a drug are modified by the presence of other drugs. DDIExtraction2011 proposes a first challenge task, Drug-Drug Interaction Extraction, to compare different techniques for DDI extraction ...
Mola Velasco, Santiago Moisés +3 more
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