Results 81 to 90 of about 6,568,172 (215)

Evaluation of RNA Secondary Stem-Loop Structures in the UTRs of Mouse Hepatitis Virus as New Therapeutic Targets

open access: yesPathogens
MHV-A59 is a beta-coronavirus that causes demyelinating encephalitis and hepatitis in mice. Recently, the mouse infection model of MHV-A59 has been used as an alternative animal infection model for SARS-CoV and SARS-CoV-2, aiding the development of new ...
Gyuhyun Kang   +5 more
doaj   +1 more source

Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice Using a Validated Liquid Chromatography–Tandem Mass Spectrometry Method

open access: yesApplied Sciences
Enavogliflozin, a sodium–glucose cotransporter 2 inhibitor, was approved in 2022 by the Korean Ministry of Food and Drug Safety as a therapeutic agent for type 2 diabetes mellitus and has been investigated for expanded therapeutic efficacy in diabetic ...
Minyeong Pang   +3 more
doaj   +1 more source

An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates

open access: yes, 2004
In the early drug discovery process, metabolic stability and cytochrome P450 inhibition are often used as an early selection tool to identify useful compounds for further development. The reliability of the data in this process is therefore crucial.
Sjöberg, H   +3 more
core   +1 more source

‘Civil society involvement in drug policy’ webinar.

open access: yes, 2018
On 30th November 2018, Ana Liffey Drug Project hosted a webinar about Civil Society Involvement in Drug Policy. The event included interviews with: Anna Quigley (CityWide) Tony Duffin (Ana Liffey Drug Project) Aoife Frances (National Family Support ...

core  

Training toolkit on drug policy advocacy.

open access: yes, 2013
This training toolkit has been developed by the International Drug Policy Consortium (IDPC) and the Eurasian Harm Reduction Network (EHRN) to build the capacity of civil society organisations for engaging with, and influencing, drug policy making ...

core  

Pantoprazole – safety in drug-drug interaction

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of review. To carry out comparative analysis of metabolic pathways of proton pump inhibitors (PPI), to determine the agent with lowest effect on activity of cytochrome CYP2C19 isoenzyme for improvement of safety of combined treatment by ...
E. V. Shikh, D. A. Sychev
doaj  

Drug Interaction 1. General Considerations

open access: yes, 1968
Drug interaction, modification of the effects of one drug by another, is a serious problem. This series of articles will deal with the interaction of drugs with other chemical agents, both exogenous and endogenous, as well' as those found in foods and ...
Edward A. Hartshorn
core   +1 more source

Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions

open access: yesFrontiers in Pharmacology
IntroductionPhenytoin, a widely prescribed anticonvulsant, presents clinical challenges due to its narrow therapeutic index and potential interactions with various foods, herbs, and medications.
Adriana Monserrath Orellana-Paucar   +10 more
doaj   +1 more source

Drug interaction screen in two yeast species

open access: yes, 2018
Raw cell growth measurements for drug interaction assays of 76 pairwise combinations in two yeast species. Each file contains a 64 column matrix of numbers, which corresponds to OD595 readings for one drug‐drug interaction.
Muhammad H. Zaman (203839)   +8 more
core   +1 more source

Brief strategic family therapy for adolescent drug abuse. [PDF]

open access: yes, 2003
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.

core  

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