Results 41 to 50 of about 11,447,845 (407)

Drug-drug interaction

open access: yesJornal Brasileiro de Nefrologia, 2014
A doenca renal cronica (DRC), considerada a grande epidemia deste milenio, tem prevalencia media de 11% nos paises desenvolvidos. Infelizmente, no Brasil ainda nao dispomos de dados definitivos sobre a prevalencia da DRC, contudo, estudo realizado em amostra de 24.248 individuos adultos, utilizando o criterio de DRC baseado em duas determinacoes da ...
openaire   +2 more sources

Pharmacodynamic Drug–Drug Interactions [PDF]

open access: yesClinical Pharmacology & Therapeutics, 2019
Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms are frequently misused.
Jin, Niu   +2 more
openaire   +2 more sources

Drug-Drug Interaction Predicting by Neural Network Using Integrated Similarity

open access: yesScientific Reports, 2019
Drug-Drug Interaction (DDI) prediction is one of the most critical issues in drug development and health. Proposing appropriate computational methods for predicting unknown DDI with high precision is challenging.
Narjes Rohani, C. Eslahchi
semanticscholar   +1 more source

Evidence of a clinically significant drug‐drug interaction between cannabidiol and tacrolimus

open access: yesAmerican Journal of Transplantation, 2019
Cannabidiol (CBD), a major purified nonpsychoactive component of cannabis with anticonvulsant properties, was approved by the U.S. Food and Drug Administration (FDA) in June 2018 as an adjuvant treatment for refractory epilepsy (Epidiolex; GW ...
A. Leino   +5 more
semanticscholar   +1 more source

Metabolite Measurement in Index Substrate Drug Interaction Studies: A Review of the Literature and Recent New Drug Application Reviews

open access: yesMetabolites
Background/Objectives: Index substrates are used to understand the processes involved in pharmacokinetic (PK) drug–drug interactions (DDIs). The aim of this analysis is to review metabolite measurement in clinical DDI studies, focusing on index ...
Jingjing Yu   +4 more
doaj   +1 more source

Evaluation of knowledge graph embedding approaches for drug-drug interaction prediction in realistic settings

open access: yesBMC Bioinformatics, 2019
Current approaches to identifying drug-drug interactions (DDIs), include safety studies during drug development and post-marketing surveillance after approval, offer important opportunities to identify potential safety issues, but are unable to provide ...
Remzi Çelebi   +5 more
semanticscholar   +1 more source

Potential Drug - Drug Interactions among Medications Prescribed to Hypertensive Patients [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Context: Drug-drug interactions(DDIs) are significant but avoidable causes of iatrogenic morbidity and hospital admission. Aim: To detect potential drug-drug interactions among medications received by hypertensive patients.
Nitin Kothari, Barna Ganguly
doaj   +1 more source

Report on Provider-Client Interaction From 68 Methadone Maintenance Clinics in China. [PDF]

open access: yes, 2016
Provider-client interaction is an integral of clinical practice and central to the delivery of high-quality medical care. This article examines factors related to the provider-client interaction in the context of methadone maintenance treatment (MMT ...
Cao, Xiaobin   +5 more
core   +1 more source

Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies

open access: yesEuropean journal of drug metabolism and pharmacokinetics, 2019
Darolutamide is a novel androgen receptor (AR) antagonist approved for the treatment of nonmetastatic castration-resistant prostate cancer (nmCRPC).
C. Zurth   +10 more
semanticscholar   +1 more source

Announcing the 2015 Viruses Young Investigator Prize and Graduate Student/Postdoctoral Fellow Travel Awards

open access: yesViruses, 2015
With the goal of recognizing outstanding contributions to the field of virology by early-career investigators, last year Viruses accepted nominations for a 2015 Young Investigator Prize in Virology. The target age was set at 40 and under.
Eric O. Freed
doaj   +1 more source

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