Results 1 to 10 of about 1,726,161 (159)

Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions [PDF]

open access: yesPharmaceutics, 2021
Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
openaire   +4 more sources

Drug Interactions and Drug Interaction Checkers

open access: yesAcademia Letters, 2021
This is an Academia Letters (commentary) article in which the clinical relevance of drug interactions and the importance of drug interaction checkers for clinical practice are discussed (structured abstract is not applicable for commentary article).
openaire   +1 more source

Provenance-Centered Dataset of Drug-Drug Interactions [PDF]

open access: yes, 2015
Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc.
A Callahan   +14 more
core   +3 more sources

A network inference method for large-scale unsupervised identification of novel drug-drug interactions [PDF]

open access: yes, 2013
Characterizing interactions between drugs is important to avoid potentially harmful combinations, to reduce off-target effects of treatments and to fight antibiotic resistant pathogens, among others.
Guimera, Roger, Sales-Pardo, Marta
core   +4 more sources

Prevalence and patterns of higher-order drug interactions in Escherichia coli. [PDF]

open access: yes, 2018
Interactions and emergent processes are essential for research on complex systems involving many components. Most studies focus solely on pairwise interactions and ignore higher-order interactions among three or more components.
Cruz-Loya, Mauricio   +7 more
core   +2 more sources

Neuronal stem cell-drug interactions : a systematic review and meta-analysis [PDF]

open access: yes, 2019
Stem cell therapy is a promising treatment option for neurodegenerative diseases that mostly affect geriatric patients who often suffer from comorbidities requiring multiple medications.
Boltze, Johannes   +4 more
core   +1 more source

Synergistic drug combinations from electronic health records and gene expression. [PDF]

open access: yes, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William   +19 more
core   +2 more sources

Choosing the safest acute combination therapy during prophylactic treatment. pharmacokinetic and pharmacodynamic considerations [PDF]

open access: yes, 2015
Drugs used in the treatment of migraine have been recently reported to be highly associated with the occurrence of clinically significant drug-drug interactions (DDIs)
Lionetto, Luana, MARTELLETTI, Paolo
core   +1 more source

Predicting Drug-Target Interactions Using Drug-Drug Interactions

open access: yesPLoS ONE, 2013
Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs. Recently, with the accumulation of drug-related data sets related to drug side effects and pharmacological data, it has became possible to predict potential drug-
Shinhyuk Kim, Hyunju Lee, Daeyong Jin
openaire   +6 more sources

Current trends in drug metabolism and pharmacokinetics. [PDF]

open access: yes, 2019
Pharmacokinetics (PK) is the study of the absorption, distribution, metabolism, and excretion (ADME) processes of a drug. Understanding PK properties is essential for drug development and precision medication.
Abduljalil   +332 more
core   +1 more source

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