Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions [PDF]
Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
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Drug Interactions and Drug Interaction Checkers
This is an Academia Letters (commentary) article in which the clinical relevance of drug interactions and the importance of drug interaction checkers for clinical practice are discussed (structured abstract is not applicable for commentary article).
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Provenance-Centered Dataset of Drug-Drug Interactions [PDF]
Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc.
A Callahan+14 more
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A network inference method for large-scale unsupervised identification of novel drug-drug interactions [PDF]
Characterizing interactions between drugs is important to avoid potentially harmful combinations, to reduce off-target effects of treatments and to fight antibiotic resistant pathogens, among others.
Guimera, Roger, Sales-Pardo, Marta
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Prevalence and patterns of higher-order drug interactions in Escherichia coli. [PDF]
Interactions and emergent processes are essential for research on complex systems involving many components. Most studies focus solely on pairwise interactions and ignore higher-order interactions among three or more components.
Cruz-Loya, Mauricio+7 more
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Neuronal stem cell-drug interactions : a systematic review and meta-analysis [PDF]
Stem cell therapy is a promising treatment option for neurodegenerative diseases that mostly affect geriatric patients who often suffer from comorbidities requiring multiple medications.
Boltze, Johannes+4 more
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Synergistic drug combinations from electronic health records and gene expression. [PDF]
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William+19 more
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Choosing the safest acute combination therapy during prophylactic treatment. pharmacokinetic and pharmacodynamic considerations [PDF]
Drugs used in the treatment of migraine have been recently reported to be highly associated with the occurrence of clinically significant drug-drug interactions (DDIs)
Lionetto, Luana, MARTELLETTI, Paolo
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Predicting Drug-Target Interactions Using Drug-Drug Interactions
Computational methods for predicting drug-target interactions have become important in drug research because they can help to reduce the time, cost, and failure rates for developing new drugs. Recently, with the accumulation of drug-related data sets related to drug side effects and pharmacological data, it has became possible to predict potential drug-
Shinhyuk Kim, Hyunju Lee, Daeyong Jin
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Current trends in drug metabolism and pharmacokinetics. [PDF]
Pharmacokinetics (PK) is the study of the absorption, distribution, metabolism, and excretion (ADME) processes of a drug. Understanding PK properties is essential for drug development and precision medication.
Abduljalil+332 more
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