Results 11 to 20 of about 896,459 (312)

Drug-drug interactions with raltegravir

open access: yesEuropean Journal of Medical Research, 2009
Objective To review all currently published drug-drug interaction studies with the HIV-integrase inhibitor raltegravir. Methods A PubMed search was conducted for all published reports up to August 1, 2009 as well as a review of updated European and US ...
Burger David M
doaj   +5 more sources

Drug Interactions and Drug Interaction Checkers

open access: yesAcademia Letters, 2021
This is an Academia Letters (commentary) article in which the clinical relevance of drug interactions and the importance of drug interaction checkers for clinical practice are discussed (structured abstract is not applicable for commentary article).
openaire   +1 more source

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit

open access: yesNature Communications, 2018
SAMHD1 is a critical restriction factor for HIV-1 and its antiviral activity is regulated by T592 phosphorylation. Here, Schott et al. show that the phosphatase PP2A-B55α dephosphorylates SAMHD1 during mitotic exit, rendering it antivirally active in G1 ...
Kerstin Schott   +14 more
doaj   +1 more source

The impact of CYP2C19 genotype on phenoconversion by concomitant medication

open access: yesFrontiers in Pharmacology, 2023
Introduction: Pharmacogenetics-informed drug prescribing is increasingly applied in clinical practice. Typically, drug metabolizing phenotypes are determined based on genetic test results, whereupon dosage or drugs are adjusted.
Laura M. de Jong   +11 more
doaj   +1 more source

Evaluation of potential drug-drug interactions in medical wards of a referral university hospital in southern part of Iran: a retrospective observational study [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2021
Introduction: Drug-drug interactions impose several financial and medical burden on medical system and can lead to various health problems. The aim of this study was to investigate the incidence of Potential Drug-Drug Interactions (PDDIs) and its related
Farzaneh Foroughinia   +2 more
doaj   +1 more source

Data-driven prediction of adverse drug reactions induced by drug-drug interactions

open access: yesBMC Pharmacology and Toxicology, 2017
Background The expanded use of multiple drugs has increased the occurrence of adverse drug reactions (ADRs) induced by drug-drug interactions (DDIs). However, such reactions are typically not observed in clinical drug-development studies because most of ...
Ruifeng Liu   +5 more
doaj   +1 more source

Herbal - Synthetic Drug Interactions

open access: yesMagna Medika, 2023
Background:  Herbal medicine is currently one of the therapeutic options chosen by the community because it is considered relatively safer and has minimal side effects.
Kintoko Kintoko   +7 more
doaj   +1 more source

Drug–Drug–Gene Interactions in Cardiovascular Medicine

open access: yesPharmacogenomics and Personalized Medicine, 2022
Innocent G Asiimwe, Munir Pirmohamed The Wolfson Centre for Personalized Medicine, MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool ...
Asiimwe IG, Pirmohamed M
doaj  

Drug–Cannabinoid Interactions in Selected Therapeutics for Symptoms Associated with Epilepsy, Autism Spectrum Disorder, Cancer, Multiple Sclerosis, and Pain

open access: yesPharmaceuticals
Clinical practice entails a translation of research that assists in the use of scientific data and therapeutic evidence for the benefit of the patient. This review critically summarizes the potential impact of cannabinoids in conjunction with other drugs
Maria G. Campos   +6 more
doaj   +1 more source

Potential drug-drug interactions and prescription errors in COVID-19 infected patients

open access: yesPublic Health and Toxicology, 2023
Introduction Prescription errors can cause havoc during the pandemic, especially for comorbid patients with diabetes and hypertension identified as a risky population group for COVID-19.
Syeda R. Tasfia   +6 more
doaj   +1 more source

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