Results 21 to 30 of about 454,627 (348)

Real-World Amount of Clotting Factor Concentrates Dispensed and Annual Medical Expenditures for Japanese Patients with Hemophilia B

open access: yesJournal of Blood Medicine, 2023
Katsuyuki Fukutake,1,2 Kanae Togo,3 Linghua Xu,3 Leona E Markson,4 José Maria Jimenez Alvir,5 Ian Winburn,6 Toshiyuki Karumori3 1Laboratory Medicine, Tokyo Medical University, Shinjuku, Tokyo, Japan; 2Department of Blood Coagulation Diseases, Ogikubo ...
Fukutake K   +6 more
doaj  

ERGONOMICS IN DRUG LABELING

open access: yesErgodesign & HCI, 2015
This article presents the study that aimed to analyze the visual ergonomic standards related to the drugs labels, especially the guidelines that point to aspects of readability. It started from the problematic that sought to understand whether the issues
Arina Blum   +2 more
doaj   +1 more source

Clinical pharmacology information in regulatory submissions and labeling: A comparative analysis of orphan and non‐orphan drugs approved by the FDA

open access: yesClinical and Translational Science, 2022
Clinical pharmacology is an integral discipline supporting the development, regulatory evaluation, and clinical use of drugs for the treatment of both common and rare diseases.
Julie Hsieh   +4 more
doaj   +1 more source

Findings on In Vitro Transporter-Mediated Drug Interactions and Their Follow-Up Actions for Labeling: Analysis of Drugs Approved by US FDA between 2017 and 2021

open access: yesPharmaceutics, 2022
Understanding possible follow-up actions on in vitro findings helps determine the necessity of labeling for drug interactions. We analyzed information for in vitro findings on transporter-mediated interactions of drugs approved by the U.S.
Kyeong-Ryoon Lee   +4 more
doaj   +1 more source

A Comparative Study of Drug Package Inserts of High Selling Cardiac Drugs against the Drug Regulations of Iranian Food and Drug Administration [PDF]

open access: yesTaṣvīr-i salāmat, 2019
Background and Objectives: The Drug Package Insert (PI) is a written information provided by drug manufacturers to deliver essential information for the consumer.
Sedigheh Mirzadeh Qasabeh   +1 more
doaj  

Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]

open access: yes, 2014
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core   +3 more sources

Current practices in organization of anesthesia drug tray

open access: yesAsian Journal of Medical Sciences, 2022
Background: The risk of medication error is high in the operating room, since the anesthesiologist prepares, stores, and administers the medication. Poor labeling practices and cluttered drug trays increase the risk of syringe swap and medication error ...
Sowmya Jois   +4 more
doaj   +1 more source

Punishing Pharmaceutical Companies for Unlawful Promotion of Approved Drugs: Why the False Claims Act is the Wrong Rx [PDF]

open access: yes, 2008
This article criticizes the shift in focus from correction and compliance to punishment of pharmaceutical companies allegedly violating the Food, Drug, & Cosmetic Act (FD&C Act) prohibitions on unlawful drug promotion.
Girard, Vicki W.
core   +2 more sources

Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]

open access: yes, 2006
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M.   +3 more
core   +2 more sources

GPCR structural characterization by NMR spectroscopy in solution

open access: yesActa Biochimica et Biophysica Sinica, 2022
In the human proteome, 826 G-protein-coupled receptors (GPCRs) interact with extracellular stimuli to initiate cascades of intracellular signaling. Determining conformational dynamics and intermolecular interactions are key to understand GPCR function as
Yang Lingyun   +2 more
doaj   +1 more source

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