Results 21 to 30 of about 29,921 (309)

Controlled release from polyurethane films: Drug release mechanisms [PDF]

, 2021
In this study, polyurethane-films loaded with diclofenac were used to analyze the drug release kinetics and mechanisms. For this purpose, the experimental procedures were developed under static and dynamic conditions with different initial drug loads of ...
SHIRINBAYAN, Mohammadali, Abbas Tcharkhtchi, Mohammadali Shirinbayan, Erfan Salahinejad, Farid Bakir, SALAHINEJAD, Erfan, Navideh Abbasnezhad, Nader Zirak, ZIRAK, Nader, BAKIR, Farid, TCHARKHTCHI, Abbas, KOUIDRI, SMAINE, ABBASNEZHAD, Navideh, Smaine Kouidri   +13 more
core   +1 more source

Influence of Concentration of Selected Cationic Surfactants on Drug Liberation

, 2010
Drug liberation-release from the dosage form is a primary cause of the movement of a drug in the body.
D. ANTONYOVÁ, J. OREMUSOVÁ, Z. VITKOVÁ, P. HERDOVÁ, M. ŽABKA   +4 more
core   +1 more source

Oral pulsatile drug delivery systems

, 2005
In the field of modified release, there has been a growing interest in pulsatile delivery, which generally refers to the liberation of drugs following a programmable lag phase from the time of administration. In particular, the recent literature reports
A. Maroni, M.E. Sangalli, L. Zema, M. Cerea   +3 more
core   +1 more source

In Vitro Liberation of Indomethacin from Chitosan Gels Containing Microemulsion in Different Dissolution Mediums

, 2014
:The objective of this research is to outline the liberation of indomethacin from different chitosan gels containing O/W microemulsion. The influence of surfactant, sodium lauryl sulfate, in two concentrations (0.5% and 0.75%, w/w) was determined in ...
Bartoníková, Kamila, Vitková, Mária, Lenka Starýchová, Mária Čuchorová, Žabka, Marián, Čierna, Martina, Mária Vitková, Špaglová, Miroslava, Starýchová, Lenka, Čuchorová, Mária, Miroslava Špaglová, Klára Gardavská, Kamila Bartoníková, Gardavská, Klára, Martina Čierna, Marián Žabka   +15 more
core   +1 more source

Perceived impacts of North Americas first de-medicalized safer supply program

Substance Abuse Treatment, Prevention, and Policy
Background The Drug User Liberation Front led an evaluation of a non-medicalized model of safer supply known as a “Compassion Club.” This club sourced, rigorously tested, packaged, and accurately labeled certain illicit substances and then provided them ...
Jeremy Kalicum, Eris Nyx, Mary Clare Kennedy, Thomas Kerr   +3 more
doaj   +1 more source

Study of dissolution profiles of Аmlodipine tablets with enalapril

Ukrainian Scientific Medical Youth Journal, 2022
quality assurance in the production of medicines is a comprehensive concept. The quality of medicines must be guaranteed at all stages of production - from development, research and production to implementation and optimal use.
Nataliia Behei, Oksana Tryhubchak
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Noradrenaline Liberation from the Dog Heart In Vivo

, 1973
The liberation of radioactive noradrenaline from the heart was studied in anesthetized open-chest dogs after a single injection of tritiated noradrenaline (15 μCi/kg in 1 ml Ringer) into the left anterior descending coronary artery.
Jacques de Champlain, Nobuharu Yamaguchi, Reginald Nadeau   +2 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source