Results 11 to 20 of about 3,936,025 (295)

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

open access: yesMedComm, 2023
Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older ...
Yujian Chen   +7 more
doaj   +1 more source

WGCNA and molecular docking identify hub genes for cardiac aging

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundCardiac aging and ageing-related cardiovascular diseases remain increase medical and social burden. Discovering the molecular mechanisms associated with cardiac aging is expected to provide new perspectives for delaying aging and related ...
Ping Ping   +8 more
doaj   +1 more source

Sex hormones and physical function among the Chinese oldest-old and centenarian women

open access: yesJournal of Translational Medicine, 2022
Background Physical independence is crucial for overall health in the elderly individuals. The life expectancy of women has been shown to be higher than that of men, which is also known as the “male–female health-survival paradox”.
Qiao Zhu   +7 more
doaj   +1 more source

NAV-001, a high-efficacy antibody-drug conjugate targeting mesothelin with improved delivery of a potent payload by counteracting MUC16/CA125 inhibitory effects

open access: yesPLoS ONE, 2023
Subsets of tumor-produced cell surface and secreted proteins can bind to IgG1 type antibodies and suppress their immune-effector activities. As they affect antibody and complement-mediated immunity, we call these proteins humoral immuno-oncology (HIO ...
N. Nicolaides, J. Kline, L. Grasso
semanticscholar   +1 more source

Prevalence and correlates of malnutrition risk among Chinese centenarians and oldest-old adults

open access: yesiScience, 2023
Summary: This study was to explore epidemiological characteristics of malnutrition and factors associated with malnutrition in centenarians and oldest-old adults, so as to provide a reference for family members and government departments to take ...
Songmei Han   +7 more
doaj   +1 more source

Silver-hollow mesoporous silica nanoparticles for clarithromycin delivery in an animal model of helicobacter pylori [PDF]

open access: yesNanomedicine Journal
Background: Nanoparticle-based drug delivery systems offer a promising approach to overcoming antimicrobial resistance and enhancing therapeutic efficacy.Objective(s): This study aimed to evaluate the efficacy of silver-hollow mesoporous silica ...
Soroush Mirfakhraee   +2 more
doaj   +1 more source

Potential use of the S-protein–Angiotensin converting enzyme 2 binding pathway in the treatment of coronavirus disease 2019

open access: yesFrontiers in Public Health, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes coronavirus disease 2019 (COVID-19), infects humans through a strong interaction between the viral spike protein (S-protein) and angiotensin converting enzyme 2 (ACE2)
Long Feng   +8 more
doaj   +1 more source

An Overview of In Vitro Drug Release Methods for Drug-Eluting Stents

open access: yesPolymers, 2022
The drug release profile of drug-eluting stents (DESs) is affected by a number of factors, including the formulation, design, and physicochemical properties of the utilized material.
N. Abbasnezhad   +4 more
semanticscholar   +1 more source

On dissolution test for Hypertril tablets using high performance liquid chromatography

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Particular attention is paid to the release of the active ingredients of drugs in the form of tablets. Therefore, we have developed a method for determining the dissolution test, for the original drug Hypertril. The purpose.
L. I. Kucherenko   +4 more
doaj   +1 more source

Manufacturing and Examination of Vaginal Drug Delivery System by FDM 3D Printing

open access: yesPharmaceutics, 2021
Vaginal drug delivery systems can provide a long-term and constant liberation of the active pharmaceutical ingredient even for months. For our experiment, FDM 3D printing was used to manufacture the vaginal ring samples from thermoplastic polyurethane ...
P. Arany   +10 more
semanticscholar   +1 more source

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