Results 91 to 100 of about 1,207,344 (315)

Drug stockpiling behavior and its impact on anxiety among the general public in the early stage after the lifting of China’s Zero-COVID policy: results from a web-based survey

Frontiers in Pharmacology
BackgroundOn 7 December 2022, China lifted most of the restrictions under the so-called zero-COVID policy due to factors like less toxicity of the new variants of the virus, leading to widespread infections throughout China.ObjectivesThis study aims to ...
Yu Huang, Shuiyang Xu, Xiang Zhao, Lei Wang, Qiaohong Lv, Suxian Wu, Qingqing Wu, Xuehai Zhang   +7 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Pharmaceutical Management and Prescribing Pattern of Antimalarial Drugs in the Public Health Facilities in Dar-es-salaam, Tanzania [PDF]

, 2011
Despite the efforts of minimizing utilization of limited financial resources in Tanzania, there are still some factors that affect the whole system of supply chain of antimalarial medicines.
Silumbe, Richard S
core  

FAIR data management: what does it mean for drug discovery? [PDF]

The drug discovery community faces high costs in bringing safe and effective medicines to market, in part due to the rising volume and complexity of data which must be generated during the research and development process.
Gribbon, Philip, Satagopam, Venkata P., Gu, Wei, Henderson, David A., Sansone, Susanna Assunta, Gadiya, Yojana, Rocca-Serra, Philippe, Ioannidis, Vassilios   +7 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Anti-drug efforts ‘undermined by bureaucracy’. [PDF]

, 2012
The bureaucratic obsession with management objectives is undermining efforts to combat drug misuse, according to the head of the Southern Regional Drug Task Force.
O'Keeffe, Cormac
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Injectable drugs for weight management

Australian Prescriber
Obesity management is complex; medications must be used in conjunction with behavioural changes and monitoring by health professionals. Injectable drugs for weight management include glucagon-like peptide-1 (GLP-1) receptor agonists (e.g. liraglutide, semaglutide) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (e.g.
Natasha Yates, Terri-Lynne South
openaire   +3 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Willingness to Pay for Drug Rehabilitation: Implications for Cost Recovery [PDF]

Objectives: This study estimates the value that clients place on drug rehabilitation services at the time of intake and how this value varies with the probability of success and availability of social services.
Jody Sindelar, David Bishai
core