Results 91 to 100 of about 23,893,303 (352)

Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats

Annals of Intensive Care, 2017
Background Crush syndrome (CS) is a serious medical condition characterized by muscle cell damage resulting from decompression after compression (i.e., ischemia/reperfusion injury).
Isamu Murata, Yuji Abe, Yuka Yaginuma, Kayako Yodo, Yuka Kamakari, Yurika Miyazaki, Daichi Baba, Yuko Shinoda, Toru Iwasaki, Kunihiko Takahashi, Jun Kobayashi, Yutaka Inoue, Ikuo Kanamoto   +12 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Pain management in drug users

, 2002
The injecting drug user is likely to present as an emergency hospital admission as a result of drug use, associated problems or lifestyle-related issues. Nurses are, therefore, increasingly likely to have to care for drug users and specifically injecting
Davison, Sarah, McCreaddie, May
core  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Decriminalisation of drug use and possession in Australia – A briefing note. [PDF]

, 2016
Currently there is debate about how Australia could better respond to illegal drugs and the associated harm. One frequently raised option is “decriminalisation of drug use and possession”.
Barratt, M, Moxham-Hall, V, Hughes, C ; https://orcid.org/, Barratt, M ; https://orcid.org/, Chalmers, J, Ritter, A ; https://orcid.org/, Hughes, C, Ritter, A, Lancaster, K ; https://orcid.org/, Lancaster, K, Moxham-Hall, V ; https://orcid.org/   +10 more
core   +1 more source

Clinical considerations of drug management in chronic cardiovascular and respiratory disorders in perioperative healthcare [PDF]

Hospital Pharmacology, 2018
Introduction: Perioperative healthcare represents the care of the patient's health, before, during and after surgical intervention. There is a lot of clinical studies that confirm high incidence of cardiovascular and respiratory events during ...
Živanović Dejan B., Rakanović Dragan M.   +1 more
doaj  

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Taking stock: A decade of drug policy - A civil society shadow report. [PDF]

, 2018
Taking stock: A decade of drug policy’ evaluates the impacts of drug policies implemented across the world over the past decade, using data from the United Nations (UN), complemented with peer-reviewed academic research and grey literature reports from ...

core  

Expert consensus on prevention and management of nausea and vomiting associated with CLDN18.2-targeted therapeutic drugs (2026 edition)

Zhongguo aizheng zazhi
Claudin 18.2 (CLDN18.2) has emerged as an important therapeutic target in gastrointestinal malignancies, particularly gastric cancer, adenocarcinoma of gastroesophageal junction, and pancreatic cancer.
Antitumor Drug Safety Management Professional Committee of Shanghai Anti-Cancer Association
doaj