Results 11 to 20 of about 848,131 (265)
Journal of Pharmaceutical Health Care and Sciences, 2023 Background Tedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resistant Staphylococcus aureus and other species.
Daisuke Negishi +5 more
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Toxicology Reports, 2014 Background: Ticagrelor is an orally available, direct acting and reversible P2Y12 receptor antagonist approved for treatment of acute coronary syndrome.
David A. Brott +7 more
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Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health
Frontiers in Nutrition, 2022 Vitamin B consists of a group of water-soluble micronutrients that are mainly derived from the daily diet. They serve as cofactors, mediating multiple metabolic pathways in humans.
Zhijie Wan +13 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2007 Purpose. GroB-T, a human CXC chemokine, has been studied for its potential to mobilize stem cells. Chemokines bind specifically to receptors on target immune cells but also to a homologous erythrocyte blood group antigen, the Duffy Antigen/Receptor for ...
Timothy W Hepburn +4 more
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Evaluation of dosing strategy for pembrolizumab for oncology indications
Journal for ImmunoTherapy of Cancer, 2017 Background Traditionally, most monoclonal antibodies (mAbs) have been dosed based on body weight because of perceived contribution of body size in pharmacokinetic variability.
Tomoko Freshwater +6 more
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The heterogeneity among subgroups of haplogroup J influencing Alzheimer’s disease risk
Journal of Advanced Research, 2021 Introduction: The impact of mitochondrial haplogroups on Alzheimer’s disease (AD) risk has not been fully elucidated and warrants further investigation at the subgroup level.
HaoChen Liu +4 more
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Journal of Lipid Research, 1994 The novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor CP-113,818 has been characterized in vitro against ACAT isolated from liver and intestine from a variety of species including human subjects, and in vivo in cholesterol-fed rats, hamsters ...
C A Marzetta +9 more
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Journal of Pharmaceutical Health Care and Sciences, 2021 Background Although the over-the-counter H1 receptor antagonist diphenhydramine is not a common drug of abuse, it was recently recognized as one of the substances causing acute poisoning in patients attempting suicide that led to admissions to our ...
Koichiro Adachi +5 more
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The Aggravation of Clozapine-Induced Hepatotoxicity by Glycyrrhetinic Acid in Rats
Journal of Pharmacological Sciences, 2014 Clozapine (CLZ) was reported to be associated with hepatotoxicity. Glycyrrhetinic acid (GA) has a liver protective effect. Our preliminary experiments showed that GA aggravated rather than attenuated CLZ-induced hepatotoxicity in primary cultured rat ...
Ling-ling Jia +12 more
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Emerging new therapeutic antibody derivatives for cancer treatment
Signal Transduction and Targeted Therapy, 2022 Monoclonal antibodies constitute a promising class of targeted anticancer agents that enhance natural immune system functions to suppress cancer cell activity and eliminate cancer cells.
Shijie Jin +7 more
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