Results 191 to 200 of about 6,868,569 (338)

Canine duodenal organoids as a functional platform for intestinal CYP regulation and drug metabolism studies. [PDF]

Drug Metab Dispos
Nakazawa M, Court MH, Ambrosini YM.
europepmc   +1 more source

The influence of gut microbiota on drug metabolism and toxicity

Expert Opinion on Drug Metabolism & Toxicology, 2016
Houkai Li, Jiaojiao He, Wei Jia
semanticscholar   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Impact of <i>Ficus deltoidea</i> Aqueous Extract on Maternal Hepatic Drug Metabolism and Foetal Development in Rats. [PDF]

Plants (Basel)
Muhammad H, Nik Zainuddin NAS, Md Saad WM, Omar MH, Lokman EF.   +4 more
europepmc   +1 more source

Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism

Drug Metabolism And Disposition, 2016
T. Tracy, Amarjit S. Chaudhry, B. Prasad, K. Thummel, E. Schuetz, Xiao-bo Zhong, Yun‐chen Tien, Hyunyoung Jeong, Xian Pan, L. Shireman, Jessica Tay-Sontheimer, Yvonne S. Lin   +11 more
semanticscholar   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

Editorial: Non-invasive methods in drug metabolism and transport: insights from biological samples to oral administration. [PDF]

Front Pharmacol
Wróblewski K, Zheng Y, Yue X.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Applications of PBPK Modeling to Estimate Drug Metabolism and Related ADME Processes in Specific Populations. [PDF]

Pharmaceutics
Gonnabathula P, Li M, Nagumalli SK, Mehta D, Fairman K.   +4 more
europepmc   +1 more source

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

Pharmacological Reviews, 2016
J. Backman, Anne M. Filppula, M. Niemi, P. Neuvonen   +3 more
semanticscholar   +1 more source