Results 21 to 30 of about 1,426,819 (145)

Safety and effectiveness of all-oral and injectable-containing, bedaquiline-based long treatment regimen for pre-XDR tuberculosis in Vietnam

open access: yesFrontiers in Pharmacology, 2022
Background: The World health organization (WHO) recently recommended standardized all-oral shorter regimens for rifampicin resistant Tuberculosis (RR-TB).
Thi Mai Phuong Nguyen   +8 more
doaj   +1 more source

Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]

open access: yes, 2017
Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu   +7 more
core   +4 more sources

Effects of Silymarin on the In Vivo Pharmacokinetics of Simvastatin and Its Active Metabolite in Rats

open access: yesMolecules, 2019
Herein, the effect of silymarin pretreatment on the pharmacokinetics of simvastatin in rats was evaluated. To ensure the accuracy of the results, a rapid and sensitive UPLC−MS/MS method was established for simultaneous quantification of simvastatin
Ying Li   +5 more
doaj   +1 more source

Community sewage sensors towards evaluation of drug use trends: detection of cocaine in wastewater with DNA-directed immobilization aptamer sensors [PDF]

open access: yes, 2016
Illicit drug use has a global concern and effective monitoring and interventions are highly required to combat drug abuse. Wastewater-based epidemiology (WBE) is an innovative and cost-effective approach to evaluate community-wide drug use trends ...
Castrignanò, Erika   +4 more
core   +1 more source

In-line NIR spectroscopy for the understanding of polymer-drug interaction during pharmaceutical hot-melt extrusion [PDF]

open access: yes, 2012
The aim was to evaluate near-infrared spectroscopy for the in-line determination of the drug concentration, the polymer-drug solid-state behaviour and molecular interactions during hot-melt extrusion.
Adriaensens, Peter   +7 more
core   +2 more sources

Liquid Chromatography/Tandem Mass Spectrometry for the Simultaneous Determination of Alverine and its Metabolite, Monohydroxy Alverine, in Human Plasma: Application to a Pharmacokinetic Study

open access: yesE-Journal of Chemistry, 2011
A rapid and sensitive LC-MS-MS method for the determination of alverine (ALV) and its major metabolite, monohydroxy alverine (MHA), in human plasma using imipramine as an internal standard was developed and validated. The analytes were extracted from 0.5
Rahul C. Gavhane   +5 more
doaj   +1 more source

Identification of Synthetic Cannabinoid 5F-EDMB-PICA in Suspicious Herbal Products [PDF]

open access: yesFayixue Zazhi, 2021
Objective To study the qualitative analysis strategy for unknown synthetic cannabinoid in the suspicious herbal product when no reference substance is available. Methods The synthetic cannabinoid in herbal blend was extracted with methanol.
MENG Xin, HUA Zhen-dong, JIA Wei, at al.
doaj   +1 more source

Optimal Management of the Public and Patients by Pharmacists in the Era of COVID-19: An Evidence-Based Review and Practical Recommendations

open access: yesFrontiers in Public Health, 2022
Purpose: Currently, managing the public and patients during the COVID-19 pandemic is constituting a health care challenge worldwide. Patient-oriented management is of crucial importance to promote emergency preparedness and response.
Zaiwei Song   +25 more
doaj   +1 more source

Authentication test of seasoning food materials made from turmeric using real-time PCR

open access: yesHo Chi Minh City Open University Journal of Science - Engineering and Technology, 2023
The authentication test for spices made from turmeric using real-time. This study aimed to determine whether the spice ingredients claimed to be made from turmeric actually contain turmeric, as asserted by the product.
Alfi Sophian, Ratna Purwaningsih
doaj   +1 more source

An Accurate and Effective Method for Measuring Osimertinib by UPLC-TOF-MS and Its Pharmacokinetic Study in Rats

open access: yesMolecules, 2018
Osimertinib, a new-generation inhibitor of the epidermal growth factor, has been used for the clinical treatment of advanced T790M mutation-positive tumors.
Song-Tao Dong   +8 more
doaj   +1 more source

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