Results 31 to 40 of about 1,620,802 (305)

Liquid Chromatography/Tandem Mass Spectrometry for the Simultaneous Determination of Alverine and its Metabolite, Monohydroxy Alverine, in Human Plasma: Application to a Pharmacokinetic Study

E-Journal of Chemistry, 2011
A rapid and sensitive LC-MS-MS method for the determination of alverine (ALV) and its major metabolite, monohydroxy alverine (MHA), in human plasma using imipramine as an internal standard was developed and validated. The analytes were extracted from 0.5
Rahul C. Gavhane, Ketan K. Nerurkar, Ashok M. Kalamkar, Mitesh R. Patil, Satish G. Pingale, Prafullakumar Kulkarni   +5 more
doaj   +1 more source

Safety and effectiveness of all-oral and injectable-containing, bedaquiline-based long treatment regimen for pre-XDR tuberculosis in Vietnam

Frontiers in Pharmacology, 2022
Background: The World health organization (WHO) recently recommended standardized all-oral shorter regimens for rifampicin resistant Tuberculosis (RR-TB).
Thi Mai Phuong Nguyen, Binh Hoa Nguyen, Thi Thanh Thuy Hoang, Hoang Anh Nguyen, Dinh Hoa Vu, Mai Hoa Nguyen, Bao Ngoc Nguyen, Tom Decroo, Viet Nhung Nguyen   +8 more
doaj   +1 more source

Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]

, 2003
In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver, Spöhrer, Ute, Vogeser, Michael   +2 more
core   +1 more source

Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs. [PDF]

, 2007
Parasite drug resistance is partly conferred by single-nucleotide polymorphisms (SNPs), and monitoring them has been proposed as an alternative to monitoring drug resistance.
Beck, Hans-Peter, Burki, Richard, Coppee, Jean Yves, Crameri, Andreas, Felger, Ingrid, Genton, Blaise, Huber, Eric, Laubscher, Daniel, Maire, Nicolas, Marfurt, Jutta, Mugittu, Kefas, Puijalon, Odile, Regös, Attila, Sismeiro, Odile   +13 more
core   +2 more sources

An Accurate and Effective Method for Measuring Osimertinib by UPLC-TOF-MS and Its Pharmacokinetic Study in Rats

Molecules, 2018
Osimertinib, a new-generation inhibitor of the epidermal growth factor, has been used for the clinical treatment of advanced T790M mutation-positive tumors.
Song-Tao Dong, Ying Li, Hao-Tian Yang, Yin Wu, Ya-Jing Li, Cong-Yang Ding, Lu Meng, Zhan-Jun Dong, Yuan Zhang   +8 more
doaj   +1 more source

Optimal Management of the Public and Patients by Pharmacists in the Era of COVID-19: An Evidence-Based Review and Practical Recommendations

Frontiers in Public Health, 2022
Purpose: Currently, managing the public and patients during the COVID-19 pandemic is constituting a health care challenge worldwide. Patient-oriented management is of crucial importance to promote emergency preparedness and response.
Zaiwei Song, Zaiwei Song, Zaiwei Song, Yang Hu, Yang Hu, Yang Hu, Yang Hu, Zhenyu Ren, Zhenyu Ren, Zhenyu Ren, Guanru Wang, Guanru Wang, Guanru Wang, Guanru Wang, Shuang Liu, Shuang Liu, Shuang Liu, Siqian Zheng, Siqian Zheng, Siqian Zheng, Li Yang, Li Yang, Li Yang, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +25 more
doaj   +1 more source

Trilostane in dogs [PDF]

, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza, Angles, Baker, Barker, Bell, Benchekroun, Biller, Boag, Braddock, Cerundolo, Chapman, Clemente, Dewis, Dunn, Eastwood, Feldman, Galac, Galac, Golden, Goy-Thollot, Guptill, Hurley, Ian K. Ramsey, Kenefick, Kintzer, Komanicky, Leone, Lorenz, Machida, Mantis, McGee, McGowan, McGrotty, Neiger, Neiger, Neuman, Peterson, Potts, Puddefoot, Ramsey, Ramsey, Randolph, Reusch, Robinson, Ruckstuhl, Semple, Semple, Sieber-Ruckstuhl, Sieber-Ruckstuhl, Skelly, Tebb, Teshima, Tueni, Vaughan, Wenger, Wilbur, Williams, Winterberg, Witt, Zeugswetter   +59 more
core   +1 more source

Recreational Use of Nitrous Oxide – a Growing Concern in Europe

Emerging Trends in Drugs, Addictions, and Health
Introduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais, L. Van Aerts, M. Evans-Brown, A. Gallegos, R. Christie, R. Jorge, T. Néfau, G. Planchuelo, R. Sedefov, C. Victorri-Vigneau, R. Povilanskiene, K. Grasaasen, D.F.t. Palmqvis, D. Mongan, K. Killeen, A.O. Duarte, A.S. Santos   +16 more
doaj   +1 more source

Comparative study on main compounds and hypoglycemic effects of dispensing granules of Coptidis Rhizoma and Scutellaria–Coptis herb couple with traditional decoction

Chinese Medicine, 2023
Background The clinical applications of dispensing granules (DG) have increased dramatically. However, it is controversial whether the DG has the same quality and efficacy compared with traditional decoction (TD).
Huanhuan Yu, Huilan Tang, Guang Hu, Zhu Chen, Mudan Guo, Bo Jiang, En Zhang, Changhua Hu   +7 more
doaj   +1 more source

Sertraline and Phenytoin Drug Interaction in a Geriatric Patient [PDF]

, 2017
This report presents the case of a 78-year-old man residing in a nursing home who presented with a 2-month history of increasing lethargy and confusion. These symptoms coincided with the initiation of sertraline in the patient.
Caprio, Thomas V., DiLoreto, Stefanie E., Hopkins, Heather A., Nathan, Kobi T, Ta, Nhon A.   +4 more
core   +2 more sources