Results 41 to 50 of about 820,021 (265)

Simultaneous Determination of 15 Mycotoxins in Grains by Solid Phase Extraction with Impurity Adsorption and UPLC/MSMS

Liang you shipin ke-ji, 2021
To establish a method for the simultaneous determination of 15 mycotoxins in grains by ultra performance liquid chromatography tandem mass spectrometry (UPLC/MSMS).
LIU Xiao-xiao, DING Hui, WU Fu-xiang, MIAO Qian, JI Liang-liang, PENG Tao, ZHANG Jing-jing   +6 more
doaj   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Study on the Mass Spectrometry Fragmentation Patterns for Rapid Screening and Structure Identification of Ketamine Analogues in Illicit Powders

Molecules, 2023
Ketamine analogues have been emerging in recent years and are causing severe health and social problems worldwide. Ketamine analogues use 2-phenyl-2-aminocyclohexanone as the basic structure and achieve physiological reactions similar to or even more ...
Yilei Fan, Jianhong Gao, Xianxin Chen, Hao Wu, Xing Ke, Yu Xu   +5 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Mass Fragmentation Characteristics of t-Boc Substituted Drug Precursors

Zhipu Xuebao
To circumvent the supervision of law, illicit manufacturers turn to produce drug related precursors. Among them, tert-butoxycarbonyl (t-Boc) substituted drug precursors are the most common type recently.
Cui-mei LIU, Xue-yan LIU, Zhen-dong HUA, Hao TANG, Yu DU, Wei JIA   +5 more
doaj   +1 more source

Knowledge, Attitudes and Practice of Healthcare Providers, Healthcare Regulatory Practitioners and Patients Toward Biosimilars in China: Insights From a Nationwide Survey

Frontiers in Pharmacology, 2022
Objective: With increasing numbers of biosimilars entering the market or in the approval pipeline in China, understanding the current awareness and attitudes of biosimilars still remains the first step to promote uptake.
Yang Hu, Yang Hu, Yang Hu, Yang Hu, Zaiwei Song, Zaiwei Song, Zaiwei Song, Dan Jiang, Dan Jiang, Dan Jiang, Dan Jiang, Lin Zhuo, Yinchu Cheng, Yinchu Cheng, Yinchu Cheng, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +17 more
doaj   +1 more source

Therapeutic drug monitoring: antiarrhythmic drugs [PDF]

British Journal of Clinical Pharmacology, 1998
Antiarrhythmic agents are traditionally classified according to Vaughan Williams into four classes of action. Class I antiarrhythmic agents include most of the drugs traditionally thought of as antiarrhythmics, and have as a common action, blockade of the fast‐inward sodium channel on myocardium. These agents have a very significant toxicity, and while
T J, Campbell, K M, Williams
openaire   +4 more sources

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Qualitative Analysis of Precursor Substances of Phenyl-2-Acetone and 3，4-Methylenedioxyphenyl-2-Acetone

Fayixue Zazhi
ObjectiveTo optimize and establish GC-MS, LC-MS, and infrared spectroscopy （IR） methods for analyzing 1-phenyl-2-propanone （P-2-P） and 3,4-methylenedioxyphenyl-2-propanone （MDP-2-P） precursors.MethodsEleven precursor substances of P-2-P and MDP-2-P were ...
LIU Xue-yan, JIA Wei, LIU Cui-mei, HUA Zhen-dong, MA Zhen-chuan, LI Zhi-yu   +5 more
doaj   +1 more source

Analysis of Galangin and Its In Vitro/In Vivo Metabolites via Ultra-High-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

Metabolites, 2022
Galangin, a naturally available flavonoid, induces a variety of pharmacological activities and biological effects via several mechanisms. However, in vivo metabolism of galangin has not been fully explored, which means knowledge of its pharmacodynamics ...
Feng Zhao, Yinling Ma, Jintuo Yin, Ying Li, Yanli Cao, Lantong Zhang   +5 more
doaj   +1 more source