Results 61 to 70 of about 1,620,802 (305)

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

Bayesian data assimilation to support informed decision-making in individualized chemotherapy [PDF]

, 2020
An essential component of therapeutic drug/biomarker monitoring (TDM) is to combine patient data with prior knowledge for model-based predictions of therapy outcomes.
de Wiljes, Jana, Hartung, Niklas, Huisinga, Wilhelm, Kloft, Charlotte, Maier, Corinna   +4 more
core   +2 more sources

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Qualitative Analysis of Precursor Substances of Phenyl-2-Acetone and 3，4-Methylenedioxyphenyl-2-Acetone

Fayixue Zazhi
ObjectiveTo optimize and establish GC-MS, LC-MS, and infrared spectroscopy （IR） methods for analyzing 1-phenyl-2-propanone （P-2-P） and 3,4-methylenedioxyphenyl-2-propanone （MDP-2-P） precursors.MethodsEleven precursor substances of P-2-P and MDP-2-P were ...
LIU Xue-yan, JIA Wei, LIU Cui-mei, HUA Zhen-dong, MA Zhen-chuan, LI Zhi-yu   +5 more
doaj   +1 more source

Rapid screening of 15 highly toxic pesticide residues in Angelica sinensis decoctions by thermal desorption electrospray ionization mass spectrometry

Food and Agricultural Immunology, 2022
A decoction is the most common form of Chinese herbal medicine dosing. An Angelica sinensis decoction was qualitatively and semi-quantitatively analyzed for 15 highly toxic pesticide residues by thermal desorption electrospray ionization mass ...
Hongyan Zhang, Qiaoying Chang, Xingzhi Wang, Jian Li, Guoyu Qiu, Fuxiang Wu, Renyuan Zhu, Ming Su   +7 more
doaj   +1 more source

Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post-repeated-Praziquantel Treatment [PDF]

, 2014
Two Kato-Katz thick smears (Kato-Katzs) from a single stool are currently recommended for diagnosing Schistosoma mansoni infections to map areas for intervention. This ‘gold standard’ has low sensitivity at low infection intensities.
A Koukounari, A Koukounari, Alan Fenwick, AP Plaisier, B Erko, BJ Vennervald, CD Criscione, CJ Standley, CM Gower, D De Clercq, D Engels, D Rollinson, David W. Oguttu, DD Lin, DG Colley, HL Shane, IM Cesari, J Utzinger, J Utzinger, J Utzinger, Joanne P. Webster, JP Webster, JR Landis, JR Stothard, JR Stothard, JS Kim, JT Coulibaly, JT Coulibaly, K Stete, L van Lieshout, L van Lieshout, LA Tchuem Tchuenté, LI Gomes, LM Siqueira, M Adriko, M Albonico, M Booth, MD French, MJ Enk, N Katz, Narcis B. Kabatereine, NB Kabatereine, PHL Lamberton, PJ Hotez, Poppy H. L. Lamberton, R Bergquist, R Grenfell, RA Ashton, RF Grenfell, RF Grenfell, S Brooker, S Knopp, S Knopp, S Knopp, SM da Frota, Stefanie Knopp, Y Zhang   +56 more
core   +5 more sources

Therapeutic drug monitoring of immunosuppressant drugs [PDF]

British Journal of Clinical Pharmacology, 1999
Individualizing a patient’s drug therapy to obtain the optimum balance between therapeutic efficacy and the occurrence of adverse events is the physician’s goal. However, achieving this goal is not always straight forward, being complicated by within and between patient variability in both pharmacokinetics and pharmacodynamics.
A, Johnston, D W, Holt
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Toward therapeutic drug monitoring of citalopram in depression? Insights from a systematic review

Frontiers in Psychiatry, 2023
BackgroundWithin the framework of individualized psychopharmacotherapy, therapeutic drug monitoring (TDM) has gained increasing relevance. In the absence of high-quality evidence, the TDM of citalopram (CIT) and the recommended therapeutic ranges of the ...
Na Xu, Na Xu, Zaiwei Song, Zaiwei Song, Zaiwei Song, Dan Jiang, Dan Jiang, Dan Jiang, Rongsheng Zhao, Rongsheng Zhao, Rongsheng Zhao   +10 more
doaj   +1 more source

Drugs and Crime in Anchorage, Alaska: A Note [PDF]

, 2005
Also published in Alaska Justice Forum 22(1): 7 (Spring 2005).This research note examines the relationship between drug use and offense charged through data collected in 2003 from 259 recent arrestees in Anchorage, Alaska using the Arrestee Drug Abuse ...
Langworthy, Robert H., McKelvie, Alan R.
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