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Hydrogel nanoparticles in drug delivery
Advanced Drug Delivery Reviews, 2008Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system (e.g., hydrophilicity and extremely high water content) with a nanoparticle (e.g., very small size).
Mehrdad, Hamidi +2 more
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Mechanised nanoparticles for drug delivery
Nanoscale, 2009Time and time again humanity is faced with a unifying global crisis that crosses the many great divides in different societies and serves to bring once segregated communities back together as a collective whole. This global community instinctively turns to science to develop the means of addressing its most pressing problems. More often than not, these
Coti, KK Coti, Karla K. +8 more
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Drug delivery and nanoparticles: Applications and hazards
International Journal of Nanomedicine, 2008 Wim H De Jong1, Paul JA Borm2,31Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; 2Zuyd University, Centre of Expertise in Life Sciences, Heerlen, The ...
Paul J A Borm, Wim H de Jong
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Drug targeting with nanoparticles
European Journal of Drug Metabolism and Pharmacokinetics, 1994Nanoparticles are colloidal polymeric particles (size < 1000 nm) to which drugs are bound by sorption, incorporation, or chemical binding. After intravenous injection they normally distribute into the organs of the reticuloendothelial system (liver, spleen, lungs, bone marrow). However, their body distribution can be altered by coating with surfactants
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Nanoparticles in cellular drug delivery
Bioorganic & Medicinal Chemistry, 2009This review highlights the properties of nanoparticles used in targeted drug delivery, including delivery to cells as well as organelle targets, some of the known pharmacokinetic properties of nanoparticles, and their typical modifications to allow for therapeutic delivery.
Amir H, Faraji, Peter, Wipf
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Nanoparticles for drug delivery in lungs
Science, 2017Biomedical Engineering Engineering drug-delivery nanoparticles for adhesion to mucus can increase their residence times in lungs. Schneider et al. alternatively developed mucus-penetrating nanoparticles that exhibit greater retention in the lung and enhanced drug-delivery capability.
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Nanoparticles for drug delivery to the lungs
Trends in Biotechnology, 2007The lungs are an attractive route for non-invasive drug delivery with advantages for both systemic and local applications. Incorporating therapeutics with polymeric nanoparticles offers additional degrees of manipulation for delivery systems, providing sustained release and the ability to target specific cells and organs. However, nanoparticle delivery
Jean C, Sung +2 more
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Functional Polymeric Nanoparticles for Drug Delivery
Current Pharmaceutical Design, 2022openaire +4 more sources
Nanoparticle Delivery of Cancer Drugs
Annual Review of Medicine, 2012Nanomedicine, the application of nanotechnology to medicine, enabled the development of nanoparticle therapeutic carriers. These drug carriers are passively targeted to tumors through the enhanced permeability and retention effect, so they are ideally suited for the delivery of chemotherapeutics in cancer treatment.
Andrew Z, Wang +2 more
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Microparticles and nanoparticles for drug delivery
Biotechnology and Bioengineering, 2006AbstractParticulate drug delivery systems have become important in experimental pharmaceutics and clinical medicine. The distinction is often made between micro‐ and nanoparticles, being particles with dimensions best described in micrometers and nanometers respectively.
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