Results 181 to 190 of about 3,856,896 (414)
Erratum to: Features, prevention and management of acute overdose due to antidiabetic drugs. Drug Saf [PDF]
, 1994 Moore Df, D. R. WOOD, GN Volans
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao +14 more
wiley +1 more source
Predicting Future Opioid Incidences Today [PDF]
arXiv, 2019 According to the Center of Disease Control (CDC), the Opioid epidemic has claimed more than 72,000 lives in the US in 2017 alone. In spite of various efforts at the local, state and federal level, the impact of the epidemic is becoming progressively worse, as evidenced by the fact that the number of Opioid related deaths increased by 12.5\% between ...
arxiv
Appraising the visibility, relevance and impacts of clinical pharmacology
British Journal of Clinical Pharmacology, EarlyView.Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers +5 more
wiley +1 more source
The Opioid Crisis: A Problem That Defies Solution? [PDF]
, 2019 Mortality resulting from drug abuse (or overdose) has tremendously increased over the past decades. Drug abuse (or overdose) has become a critical public health concerns or issue in the United States of America due to its related alarming rate of death ...
Olanrewaju, Olubunmi
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan +3 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Addressing Prescription Drug Abuse in the United States: Current Activities and Future Opportunities [PDF]
The United States is in the midst of an unprecedented drug overdose epidemic. Drug overdose death rates have increased five-fold since 1980.1 By 2009, drug overdose deaths outnumbered deaths due to motor vehicle crashes for the first time in the U.S ...
core
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza +26 more
wiley +1 more source
Poisoning and drug overdoses in the Emergency Department at Songklanagarind Hospital
Journal of Health Science and Medical Research (JHSMR), 2010 Objective: To study the prevalence of poisoning and drug overdoses in the Emergency Department (ED) Songklanagarind Hospital. Material and Methods: A Retrospective study from January 1, 2007 to December 31, 2007. The records of all patients who presented
Chaipluk Sriprapan +1 more
doaj