Results 41 to 50 of about 78,243 (311)

The impact of the novel coronavirus disease (COVID-19) pandemic on drug overdose-related deaths in the United States and Canada: a systematic review of observational studies and analysis of public health surveillance data

Substance Abuse Treatment, Prevention, and Policy, 2021
Background There are preliminary indications that the trajectory of drug overdose-related deaths in North America has been exacerbated due to the novel coronavirus disease pandemic (COVID-19).
Sameer Imtiaz, Frishta Nafeh, Cayley Russell, Farihah Ali, Tara Elton-Marshall, Jürgen Rehm   +5 more
doaj   +1 more source

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

Advanced Functional Materials, EarlyView.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra, Liwen Zhang, Tianqi Guo, Sašo Ivanovski, Ruirui Qiao, Karan Gulati   +5 more
wiley   +1 more source

Prescription drug monitoring and drug overdose mortality [PDF]

Injury Epidemiology, 2014
Background: Abuse of prescription drugs, particularly opioid analgesics, has become a major source of injury mortality and morbidity in the United States. To prevent the diversion and misuse of controlled substances, many states have implemented prescription drug monitoring programs (PDMPs).
Li, Guohua, Brady, Joanne E., Lang, Barbara, Giglio, James F., Wunsch, Hannah, DiMaggio, Charles J.   +5 more
openaire   +4 more sources

Cocaine- and opiate-related fatal overdose in New York City, 1990–2000

BMC Public Health, 2007
Background In New York City (NYC), the annual mortality rate is higher for accidental drug overdoses than for homicides; cocaine and opiates are the drugs most frequently associated with drug overdose deaths. We assessed trends and correlates of cocaine-
Tardiff Ken, Gross Charles, Piper Tinka, Bucciarelli Angela, Bernstein Kyle T, Galea Sandro   +5 more
doaj   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Estimated Number of Injection-Involved Overdose Deaths in US States From 2000 to 2020: Secondary Analysis of Surveillance Data

JMIR Public Health and Surveillance
BackgroundIn the United States, both drug overdose mortality and injection-involved drug overdose mortality have increased nationally over the past 25 years.
Eric William Hall, Patrick Sean Sullivan, Heather Bradley   +2 more
doaj   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

The impact of opioid agonist treatment on fatal and non-fatal drug overdose among people with a history of opioid dependence in NSW, Australia, 2001-2018: findings from the OATS retrospective linkage study.

International Journal of Population Data Science, 2022
Objectives There are critical periods of mortality risk at onset and cessation of opioid agonist treatment. We aim to determine whether non-fatal overdose followed the same pattern as fatal overdose, comparing the first 4 weeks of treatment and ...
Nicola Jones, Louisa Degenhardt, Matthew Hickman, Suzanne Nielsen, Sarah Larney, Timothy Dobbins, Robert Ali   +6 more
doaj   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, EarlyView.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

Psychosocial and contextual correlates of opioid overdose risk among drug users in St. Petersburg, Russia

Harm Reduction Journal, 2009
Background Opioid overdose in Russia is a problem that has grown more severe as heroin abuse expanded over the past decade, yet few studies have explored it in detail.
Ilyuk Ruslan, Krupitsky Evgeny, Blinnikova Ksenia, Torban Mikhail, Green Traci C, Grau Lauretta E, Kozlov Andrei P, Heimer Robert   +7 more
doaj   +1 more source