Results 81 to 90 of about 78,243 (311)
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli+13 more
wiley +1 more source
Drug points: Acute polyradiculoneuropathy after amitriptyline overdose [PDF]
Jerome Marley
openalex +1 more source
Who is Overdosing? An Updated Picture of Overdose Deaths From 2008 to 2015
Purpose: To determine the role of opioids in drug overdose deaths in Allen County, Indiana between January 1, 2008, and December 31, 2015. Methods: File review of 418 overdose deaths was performed using Indiana State Department of Health death ...
Gregory Eigner+6 more
doaj +1 more source
This study evaluates the role of elastin in vascular response 28 days after balloon angioplasty using uncoated and paclitaxel‐coated balloons in a healthy porcine model. The results show higher elastin content in external femoral arteries, which is inversely correlated with vascular injury, inflammation, smooth muscle cell loss, proteoglycan and fibrin
María Gracia de Garnica García+7 more
wiley +1 more source
Correction: Ketotifen overdose: surveillance of the toxicity of a new drug [PDF]
Gertrude Baker
openalex +1 more source
A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng+4 more
wiley +1 more source
Erratum to: Features, prevention and management of acute overdose due to antidiabetic drugs. Drug Saf [PDF]
Moore Df, D. R. WOOD, GN Volans
openalex +1 more source
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li+9 more
wiley +1 more source
Long‐term immunosuppression of rabbits through oral tacrolimus administration
Oral gavage of rabbits with 1.5 mg/kg/d of tacrolimus allows for an efficient long‐term (1 year) immunosuppression with minimal side effects and no loss of animals. lmmunosuppressed rabbits are a convenient animal model to investigate the long‐term efficacy of human allografts in vivo.
Alexane Thibodeau+4 more
wiley +1 more source
Strategies for optimization of hypoglycemia rat models
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher+4 more
wiley +1 more source