Results 81 to 90 of about 3,856,896 (414)

Improving the Performance of Bayesian Logistic Regression Model with Overdose Control in Oncology Dose-Finding Studies [PDF]

open access: yesarXiv, 2021
An accurately identified maximum tolerated dose (MTD) serves as the cornerstone of successful subsequent phases in oncology drug development. Bayesian logistic regression model (BLRM) is a popular and versatile model-based dose-finding design.
arxiv  

Xylazine in Overdose Deaths and Forensic Drug Reports in US States, 2019-2022

open access: yesJAMA Network Open
Key Points Question To what extent is xylazine reported in fatal overdoses and law enforcement drug submissions in different states? Findings In this cross-sectional study of US overdose deaths and forensic reports, 16 states had no xylazine forensic ...
Manuel Cano   +2 more
semanticscholar   +1 more source

Vital Signs: Characteristics of Drug Overdose Deaths Involving Opioids and Stimulants — 24 States and the District of Columbia, January–June 2019

open access: yesMMWR. Morbidity and mortality weekly report, 2020
Introduction Provisional estimates indicate that drug overdose deaths increased in 2019 after a slight decrease in 2018. In 2018, overdose deaths primarily involved opioids, with continued increases in deaths involving illicitly manufactured fentanyls ...
J. O'Donnell   +4 more
semanticscholar   +1 more source

Opioid Addiction 2016 Facts & Figures [PDF]

open access: yes, 2016
National Opioid Overdose Epidemic* Drug overdose is the leading cause of accidental death in the US, with 55,403 lethal drug overdoses in 2015. Opioid addiction is driving this epidemic, with 20,101 overdose deaths related to prescription pain relievers,

core  

Localization accuracy of 6‐second CBCT for lung IGRT with various breathing patterns

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The 6‐second cone beam computed tomography (CBCT) acquisition of the Ethos HyperSight (Varian Medical Systems, Inc. Palo Alto, CA, USA) on‐board imaging system offers benefits, but could be too fast to accurately capture an average target position in a free‐breathing lung cancer patient. This study aimed to ascertain whether a 6‐second
Jihye Koo   +5 more
wiley   +1 more source

Drug overdose in the ED: a record linkage study examining emergency department ICD-10 coding practices in a cohort of people who inject drugs

open access: yesBMC Health Services Research, 2018
Background Drug overdose is a leading cause of mortality and morbidity amongst people who inject drugs (PWID). Drug overdose surveillance typically relies on the International Classification of Diseases (ICD-10) coding system, however its real world ...
Rehana Di Rico   +3 more
doaj   +1 more source

A statistical analysis of drug seizures and opioid overdose deaths in Ohio from 2014 to 2018 [PDF]

open access: yesJournal of Student Research, Volume 10, Issue 1, 2021
This paper examines the association between police drug seizures and drug overdose deaths in Ohio from 2014 to 2018. We use linear regression, ARIMA models, and categorical data analysis to quantify the effect of drug seizure composition and weight on drug overdose deaths, to quantify the lag between drug seizures and overdose deaths, and to compare ...
arxiv   +1 more source

Drug Overdose Deaths Before and After Shelter-in-Place Orders During the COVID-19 Pandemic in San Francisco

open access: yesJAMA Network Open, 2021
This cross-sectional study evaluates the association of the shelter-in-place order with fatal drug overdoses in San Francisco, California.
Ayesha Appa   +6 more
semanticscholar   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp   +8 more
wiley   +1 more source

CDC Warns of Surge in Drug Overdose Deaths During COVID-19.

open access: yesJAMA Health Forum, 2021
Spurred by a spike in drug overdose deaths over the past year, the Centers for Disease Control and Prevention (CDC) is warning public health departments, health care professionals, and first responders of “a concerning acceleration of the increase in ...
J. Stephenson
semanticscholar   +1 more source

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