Results 31 to 40 of about 1,969,162 (302)

Evaluation of potential interactions of oral medications prescribed in a kidney and liver transplant unit

open access: yesRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2023
Objective: To identify, quantify and classify, according to the degree of severity, potential drug interactions (PDI) present in prescriptions for oral medications for patients admitted to a transplant unit.
Glaydiane Alves SOUSA   +6 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correction for potentially inappropriate prescribing can increase specificity when using drug prescriptions as an adjunct to diagnostic codes to assess comorbidities in older patients

open access: yesEpidemiology, Biostatistics and Public Health, 2022
Background: Comorbidities are a growing problem in older patients in many clinical settings, but electronic records may give an unsatisfactory picture of this complexity.
Gianfrancesco Fiorini   +5 more
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

ASSESSMENT OF PRESCRIPTION PATTERN AND PRESCRIPTION ERRORS USING THE WORLD HEALTH ORGANIZATION DRUG USE INDICATORS IN LADY READING HOSPITAL PESHAWAR, PAKISTAN: A RETROSPECTIVE STUDY

open access: yesKhyber Medical University Journal, 2018
OBJECTIVES: To assess and evaluate prescription pattern and prescription errors using World Health Organization (WHO) drug use indicators in the medical ward of Leady Reading Hospital, Peshawar, Pakistan.
Haya Hussain   +6 more
doaj  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Potential intravenous drug interactions in intensive care

open access: yesRevista da Escola de Enfermagem da USP
OBJECTIVE To analyze potential intravenous drug interactions, and their level of severity associated with the administration of these drugs based on the prescriptions of an intensive care unit.
Maiara Benevides Moreira   +3 more
doaj   +1 more source

Effect of Prescription Drug Coverage on the Elderly's Use of Prescription Drugs

open access: yesINQUIRY: The Journal of Health Care Organization, Provision, and Financing, 2009
This paper evaluates the effect of prescription drug insurance coverage on prescription drug use among the elderly. Estimates were obtained using multivariate regression and a fixed-effects (within-person) research design that controls for unmeasured person-specific effects that may confound the relationships of interest.
Nasreen Khan, Robert Kaestner
openaire   +3 more sources

Prescription Drug Monitoring and Dispensing of Prescription Opioids [PDF]

open access: yesPublic Health Reports®, 2014
Objective. In the United States, per-capita opioid dispensing has increased concurrently with analgesic-related mortality and morbidity since the 1990s. To deter diversion and abuse of controlled substances, most states have implemented electronic prescription drug monitoring programs (PDMPs).
Joanne E, Brady   +5 more
openaire   +2 more sources

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