Repositioning of drugs: Hydroxychloroquine
Vishakha Jain, OP Gupta
openaire +1 more source
From In Silico Hypothesis to Validation: The Role of Real-World Evidence in the Preliminary Verification of AI-Generated Drug-Repositioning Candidates: A Comprehensive Review. [PDF]
Gałuszewski M +4 more
europepmc +1 more source
Lateral Mucosal Flap With Steroid‐Eluting Implant in Revision Draf Type III Frontal Sinus Surgery
This technical note introduces a novel endoscopic strategy that integrates a laterally based endonasal mucosal flap with a bioabsorbable steroid‐eluting implant to prevent restenosis following revision of Draf type III frontal sinus surgery. The vascularized flap is stabilized and maintained in close apposition to the underlying bone by a self ...
Mario Turri‐Zanoni +6 more
wiley +1 more source
Targeting Cancer Cell Energy Metabolism in Colorectal Cancer: Opportunities and Challenges from Drug Repositioning. [PDF]
Tomassini L +4 more
europepmc +1 more source
Patient‐Reported Outcomes of Palatopharyngeal Surgery Without Tonsillectomy: A Meta‐Analysis
Palatopharyngeal surgery without tonsillectomy leads to clinically meaningful improvements in daytime sleepiness and snoring, but patient‐reported outcomes vary markedly by surgical technique. Suture‐based procedures, muscle relocation, cold‐steel approaches, and powered instruments show the largest and durable benefits, with no evidence of effect ...
Samuel Tschopp +4 more
wiley +1 more source
Dual-route embedding-aware graph neural networks for drug repositioning. [PDF]
Zhao Y +6 more
europepmc +1 more source
Finite Element Analysis of Upper Airway in Ansa Cervicalis Stimulation for Obstructive Sleep Apnea
We developed a subject‐specific FE model to investigate how ACS stabilizes the upper airway in OSA. Simulations demonstrate that caudal traction applied through the hyolaryngeal complex produces coordinated multilevel airway stabilization, with pronounced effects at the retropalatal and retro‐epiglottic regions under physiologic loading.
Mukund Gupta +4 more
wiley +1 more source
SMPR: a structure-enhanced multimodal drug‒disease prediction model for drug repositioning and cold start. [PDF]
Dong X +7 more
europepmc +1 more source
How Can Pharmacology Help Us Overcome the Challenges of Drug Repositioning as Antivirals to Treat Emerging Pathogens? The Example of Covid-19. [PDF]
Ben Ghezala I +5 more
europepmc +1 more source

