Results 211 to 220 of about 59,924 (341)

Repositioning salicylanilide anthelmintic drugs to treat adenovirus infections

, 2019
José Antonio Marrugal‐Lorenzo, Ana Serna‐Gallego, Judith Berastegui‐Cabrera, Jerónimo Pachón, Javier Sánchez‐Céspedes   +4 more
openalex   +1 more source

A Prospective Multi‐Center Implementation Study to Improve the Diagnosis and Treatment of Benign Paroxysmal Positional Vertigo

Academic Emergency Medicine, EarlyView.
ABSTRACT Background Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo, yet it remains underdiagnosed and undertreated in emergency departments (EDs). Despite evidence‐based guidelines recommending bedside diagnostic maneuvers (Dix‐Hallpike and supine roll test) and canalith repositioning maneuvers (CRMs), these are ...
Robert Ohle, Danielle Roy, Elger Baraku, Kashyap Patel, David W. Savage, Sarah McIsaac, Ravinder Singh, Daniel Lelli, Darren Tse, Peter Johns, Krishan Yadav, Jeffrey J. Perry   +11 more
wiley   +1 more source

Dual-route embedding-aware graph neural networks for drug repositioning. [PDF]

Brief Bioinform
Zhao Y, Chen Y, Du J, Wen J, Sun Q, Wang R, Chen C.   +6 more
europepmc   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

SMPR: a structure-enhanced multimodal drug‒disease prediction model for drug repositioning and cold start. [PDF]

J Cheminform
Dong X, Miao R, Zhang S, Jia S, Zhang L, Liang Y, Zhang J, Zhu YZ.   +7 more
europepmc   +1 more source

Drug repositioning in pulmonary arterial hypertension: challenges and opportunities [PDF]

, 2019
Daniel Grinnan, Cory R. Trankle, Adam Andruska, Bruce Bloom, Edda Spiekerkoetter   +4 more
openalex   +1 more source

Selective Pectoralis Muscle Denervation Reduces Capsular Contracture in Sub‐Pectoral Breast Reconstruction. Long‐Term Retrospective Case‐ Control Study

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Implant‐based breast reconstruction (IBBR) is the most common method of breast reconstruction globally. Although the traditional approach places implants in a retropectoral position, pre‐pectoral reconstruction has recently gained popularity due to its improved aesthetic outcomes and lower capsular contracture (CC) rates.
Marco Bernini, Federico Spolveri, Margherita Serra, Silvia Sordi, Cinzia Tommasi, Lorenzo Orzalesi, Lorenzo Tofani, Chiara Bellini, Diego De Benedetto, Jacopo Nori Cucchiari, Luca Visani, Carlotta Becherini, Viola Salvestrini, Lorenzo Livi, Icro Meattini   +14 more
wiley   +1 more source

Enhancing drug repositioning: A multi-class ensemble model for drug-target interaction prediction with action type categorization. [PDF]

PLoS One
Jafari Khouzani L, Sardari S, Jafari Khouzani S, Pérez-Sánchez H, Ghasemi F.   +4 more
europepmc   +1 more source

Drug repositioning: Progress and challenges in drug discovery for various diseases

, 2022
Yi Hua, Xiaowen Dai, Yuan Xu, Guomeng Xing, Haichun Liu, Tao Lu, Yadong Chen, Yanmin Zhang   +7 more
openalex   +2 more sources

A Comparison Study Between Electrical Muscle Stimulation and Transcutaneous Electrical Nerve Stimulation on Treatment of Myofascial Pain Syndrome

Artificial Organs, EarlyView.
Transverse placement of electrical muscle stimulation (EMS) electrodes across muscle fibers elicits localized contractions, facilitating greater active stretching (AS) of regions containing myofascial trigger points. This EMS + AS approach mimics passive stretching, with EMS providing resistance force similar to that typically applied by a therapist's ...
Seekaow Churproong, Benjamin Metcalfe, Polly Mcguigan, Dingguo Zhang   +3 more
wiley   +1 more source