Results 231 to 240 of about 60,427 (345)

Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study

, 2021
Muhammad I. Ismail, Hanan M. Ragab, Adnan A. Bekhit, Tamer M. Ibrahim   +3 more
openalex   +2 more sources

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

Small, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi, Tijana Maric, Isidro Badillo‐Ramírez, Juliane Fjelrad Christfort, Matteo Tollemeto, Carmen Milan Guimera, Casper Nisula, Giulia Zappalá, Laura De Vittorio, Marta Rubio‐Huertas, Sungyeong Kim, Ziqiao Li, Morten Bo Søndergaard Svendsen, Zhongyang Zhang, Anja Boisen   +14 more
wiley   +1 more source

How Can Pharmacology Help Us Overcome the Challenges of Drug Repositioning as Antivirals to Treat Emerging Pathogens? The Example of Covid-19. [PDF]

Clin Transl Sci
Ben Ghezala I, Peiffer-Smadja N, Solas C, Nougairède A, Touret F, Bardou M.   +5 more
europepmc   +1 more source

Repositioning of drugs: Hydroxychloroquine

Journal of Mahatma Gandhi Institute of Medical Sciences, 2015
Vishakha Jain, OP Gupta
openaire   +1 more source

A thermoplastic microfluidic platform with integrated electrospun scaffolds for assessing brain cell‐specific drug selectivity

VIEW, EarlyView.
Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa, Laura Palumbo, Martina La Rosa, Antonella Girgenti, Fabio Salvatore Palumbo, Pasquale Picone, Francesco Lopresti, Domenico Nuzzo, Vincenzo La Carruba   +8 more
wiley   +1 more source

SMPR: a structure-enhanced multimodal drug‒disease prediction model for drug repositioning and cold start. [PDF]

J Cheminform
Dong X, Miao R, Zhang S, Jia S, Zhang L, Liang Y, Zhang J, Zhu YZ.   +7 more
europepmc   +1 more source

Long‐Term Results of UPPP and Coblation Channeling of the Tongue for Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the long‐term surgical outcomes of combined uvulopalatopharyngoplasty (UPPP) and coblation channeling of the tongue (CCT) for moderate‐to‐severe obstructive sleep apnea (OSA). Methods The study enrolled patients with moderate‐to‐severe OSA who underwent treatment with UPPP plus CCT and had a minimal follow‐up of 2 years ...
Ren‐Hui Chen, Qian Cai, Wei‐Qi Chen, Xiao‐Ming Huang   +3 more
wiley   +1 more source

Drug Repositioning of Pegbing® for Essential Thrombocythemia: Insights from PK/PD Modeling and Extrapolation. [PDF]

Clin Pharmacol Ther
Jian W, Yin Y, Chen R, Xue J, Gu J, Du Z, He R, Zhou T.   +7 more
europepmc   +1 more source

Drug-Repositioning Approach for the Discovery of Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicines In Vitro: Potent High Activity of Daio-Kanzo-To [PDF]

, 2018
Ken Ichi Watanabe
openalex  

Epiglottis Collapse in Individuals With Obstructive Sleep Apnea

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repeated upper airway collapse during sleep. The epiglottis, often overlooked in conventional assessments, has emerged as a site of significant obstruction in OSA.
Dan Chen, Li Zhou, Qi‐Ying Zeng, Yu‐Yin Liu, Jia‐Jing Yang, Rui Liu, Zhi‐Hang Zhou, Fei‐Fei Chen, Li Tang, Fang‐Qi Liang, Hong‐Liang Yi, Su‐Ru Liu   +11 more
wiley   +1 more source