Results 211 to 220 of about 3,896,424 (394)
Identification of core therapeutic targets for Monkeypox virus and repurposing potential of drugs against them: An in silico approach [PDF]
, 2023 Anshuman Sahu +5 more
openalex +1 more source
Recombinant Human Neuregulin1‐β1 Significantly Reduces Schwannoma Growth in Mice
Annals of Neurology, EarlyView.rhNRGβ1‐Replacement‐Therapy: Under physiological conditions, NRGβ1 is expressed on axons (in orange), where it activates ERBB2 receptors, facilitating successful nerve regeneration following injury. However, loss of NF2 leads to a reduction in NRGβ1‐expression and increased ErbB2 levels on Schwann cells (in green), which contributes to schwannoma ...
Julia P. Bischoff +7 more
wiley +1 more source
Repurposing of drugs against methyltransferase as potential Zika virus therapies [PDF]
, 2023 Rohit Shukla +9 more
openalex +1 more source
3D Hydrogel Cell Cultures and Their Biomedical Applications
Advanced NanoBiomed Research, EarlyView.The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai +7 more
wiley +1 more source
Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT With the large‐scale construction of wastewater treatment facilities, the production of municipal sewage sludge continues to rise. This sludge contains substantial amounts of toxic and hazardous substances, and improper disposal may lead to secondary environmental pollution.
He Li +5 more
wiley +1 more source
Mining small-molecule screens to repurpose drugs [PDF]
, 2011 S. Joshua Swamidass
openalex +1 more source
Material Limitations and Processing Challenges of Bio‐Based Thermoplastics: A Review
Journal of Applied Polymer Science, EarlyView.This review highlights recent advances in bio‐based thermoplastic polymers (b‐bTPs), focusing on their composition, formulation challenges, and industrial applications. Key aspects include the use of additives and blends to improve performance, microcellular injection molding techniques, and the recyclability of b‐bTPs foams.
Catarina Faria +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló +5 more
wiley +1 more source
Integrated Stress Response and Necroptosis Drive Epithelial Dysfunction in Crohn’s Disease: Repurposing Cancer drugs for Permeability Barrier Healing [PDF]
Seema Khurana +5 more
openalex +1 more source