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COVID-19: Potential Repurposing Drugs
Infectious Disorders - Drug Targets, 2022: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the most infectious diseases and caused coronavirus disease in 2019 (COVID-19). It has been widely spread worldwide and infected more than 28 million peoples in 215 countries, and more than 920,000 have now died from COVID-19.
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Repurposing Drugs for Cancer Prevention
Current Topics in Medicinal Chemistry, 2016Development of agents for cancer prevention has been particularly challenging for two main reasons. One is the inherent difficulty in identifying targets for the heterogeneous group of processes that lead to invasive cancer arising at different target organ sites, while the other is the need for safe, tolerable interventions that can be given for ...
Daniel K, Lee, Eva, Szabo
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Drug repurposing in kidney disease
Kidney International, 2018Drug repurposing, is the re-tasking of known medications for new clinical indications. Advantages, compared to de novo drug development, include reduced cost and time to market plus the added benefit of a known pharmacokinetic and safety profiles. Suitable drug candidates are identified through serendipitous observations, data mining, or increased ...
Usha, Panchapakesan, Carol, Pollock
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In the dynamic landscape of cancer therapeutics, the innovative strategy of drug repurposing emerges as a transformative paradigm, heralding a new era in the fight against malignancies. This book chapter aims to embark on the comprehension of the strategic deployment of approved drugs for repurposing and the meticulous journey of drug repurposing from ...
Juni, Banerjee +2 more
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Juni, Banerjee +2 more
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2015
The aim of this discussion was to explore the concept and purpose of repositioning drugs, understand the boundaries that still underlie the technique and, analyze repurposed drugs, so they can serve of inspiration for the future of drug discovery and development.
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The aim of this discussion was to explore the concept and purpose of repositioning drugs, understand the boundaries that still underlie the technique and, analyze repurposed drugs, so they can serve of inspiration for the future of drug discovery and development.
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
exaly
Drug repurposing for respiratory infections
Respiratory infections such as Coronavirus disease 2019 are a substantial worldwide health challenge, frequently resulting in severe sickness and death, especially in susceptible groups. Conventional drug development for respiratory infections faces obstacles such as extended timescales, substantial expenses, and the rise of resistance to current ...Juveriya, Israr +2 more
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Drug repurposing for neurodegenerative diseases
Neurodegenerative diseases (NDDs) are neuronal problems that include the brain and spinal cord and result in loss of sensory and motor dysfunction. Common NDDs include Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS) etc.Halak, Shukla +3 more
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Drug repurposing for personalized medicine
Personalized medicine has emerged as a revolutionary approach to healthcare in the 21st century. By understanding a patient's unique genetic and biological characteristics, it aims to tailor treatments specifically to the individual. This approach takes into account factors such as an individual's lifestyle, genetic makeup, and environmental factors toJahnvi, Hora +2 more
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