Results 241 to 250 of about 1,830,783 (287)

Integrative Multi-Transcriptomic Uncovers Actionable Signatures and Drug Repurposing Candidates for ccRCC-Hypertension Comorbidity. [PDF]

Cancers (Basel)
Zhang Y, Kho BS, Wang X, Lu H, Zhu M, Zhu R, Wang Y.   +6 more
europepmc   +1 more source

The role of AI-assisted drug repurposing in neurological disorders: a systematic review of validation strategies, challenges and opportunities. [PDF]

J Nanobiotechnology
Chen F, Wang L, Liu H, Khan Q, Tang B, Bao N.   +5 more
europepmc   +1 more source

Artificial intelligence in drug research and development: a review of methods and applications in drug repurposing. [PDF]

Brief Bioinform
Zielińska A, Fornalik M, Szczepaniak M, Gimla M, Lemańska A, Cielecka-Piontek J, Souto EB.   +6 more
europepmc   +1 more source

Personalized Drug Repurposing Screen Identifies Patient-Specific Therapeutic Candidates for Mucopolysaccharidosis Type IIIB. [PDF]

J Pers Med
McDaniel KD, Ghousifam N, Bowling RA, Chen CZ, Zheng W, Shyr ZA.   +5 more
europepmc   +1 more source

Drug Repurposing in Veterinary Oncology: Myth or Reality? [PDF]

Vet Sci
Ciccarelli S, Perrone C, Cavalera MA, Giuliano A.   +3 more
europepmc   +1 more source

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Perspectives on Drug Repurposing

Current Medicinal Chemistry, 2021
Complex common diseases are a significant burden for our societies and demand not only preventive measures but also more effective, safer, and more affordable treatments. The whole process of the current model of drug discovery and development implies a high investment by the pharmaceutical industry, which ultimately impact in high drug prices.
Alejandro Schcolnik-Cabrera, Daniel Juárez-López, Alfonso Duenas-Gonzalez   +2 more
openaire   +2 more sources

Drug Repurposing for Rare Diseases [PDF]

Trends in Pharmacological Sciences, 2021
Currently, there are about 7000 identified rare diseases, together affecting 10% of the population. However, fewer than 6% of all rare diseases have an approved treatment option, highlighting their tremendous unmet needs in drug development. The process of repurposing drugs for new indications, compared with the development of novel orphan drugs, is a ...
Mieke van Haelst, Gijs van Haaften, Helen Roessler   +2 more
exaly   +3 more sources

Drug databases and their contributions to drug repurposing

Genomics, 2020
Drug repurposing is an interesting field in the drug discovery scope because of reducing time and cost. It is also considered as an appropriate method for finding medications for orphan and rare diseases. Hence, many researchers have proposed novel methods based on databases which contain different information.
Yosef Masoudi-Sobhanzadeh, Massoud Amanlou, Yadollah Omidi   +2 more
exaly   +3 more sources