Results 271 to 280 of about 3,896,424 (394)

Repurposing of FDA‐Approved Drugs to Disrupt Iron Uptake in Mycobacterium abscessus: Targeting Salicylate Synthase as a Novel Approach [PDF]

Giovanni Stelitano, C Bettoni, Matteo Mori, Mario Cocorullo, Andrea Tresoldi, Fiorella Meneghetti, Stefania Villa, Laurent R. Chiarelli   +7 more
openalex   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo, Vincenzo Patamia, Chiara Zagni, Antonio Rescifina, Giuseppe Floresta   +4 more
wiley   +1 more source

Pattern Recognition Algorithms in Pharmacogenomics and Drug Repurposing-Case Study: Ribavirin and Lopinavir. [PDF]

Pharmaceuticals (Basel)
Calvo H, Islas-Díaz D, Hernández-Laureano E.   +2 more
europepmc   +1 more source

Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics

Monika Maheshwari, Praveen Sekar, Muhasaparur Ganesan Rajanandh   +2 more
openalex   +1 more source

An integrated multimodal approach to drug repurposing in endometriosis, using ROR1 as a target. [PDF]

Front Pharmacol
Gunther K, Liu D, Stannard G, Holmes M, Loo C, Guo B, Bowden N, Abbott J, Ford CE.   +8 more
europepmc   +1 more source

Machine learning prediction of intestinal α-glucosidase inhibitors using a diverse set of ligands: a drug repurposing effort with drugBank database screening [PDF]

Adeshina I. Odugbemi, Clement Nyirenda, Alan Christoffels, Samuel Egieyeh   +3 more
openalex   +1 more source

High‐Performance Solar‐Thermal Hydrogel Based on Waste Biomass Materials for Power Generation and Water Purification

EcoEnergy, EarlyView.
An environmentally friendly and highly efficient solar evaporator was constructed using waste biomass materials and polyvinyl alcohol carrier, which achieves an outstanding evaporation rate of 1.48 kg m−2 h−1, corresponding to an energy conversion efficiency of 82.49% under 1.0 kW m−2 simulated sunlight irradiation.
Shuo Qi, Haiying Tian, Lu Han, Tianjiao Li, Zuoyu Wang, Pengfei Li, Yingyuan Zhang, Tao Jia, Xiuhua Zhao, Wai‐Yeung Wong, Nanxi Jin   +10 more
wiley   +1 more source

Drug Repurposing: An Emerging Strategy in <i>Staphylococcus aureus</i> Infections. [PDF]

J Microbiol Biotechnol
Li Y, She P, Liu Y, Guo S, Huang G, Xiao D, Wu Y.   +6 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source