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The synergistic action of reduced membrane permeability and antibiotic sequestration as a novel mechanism for carbapenem resistance in <i>Campylobacter</i>. [PDF]
Chen X +15 more
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[Drug therapy of infections and bacterial resistance].
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Drugs Resistance in Bacterial Diseases
2021The development of resistance in micro-organisms against the antimicrobial agents is known as drug resistance, and this causes morbidity and mortality in humans and animals. Major contributing factors for the development of drug resistance are the overuse of antibiotics, inaccurate implementation, extended hospitalization, and unintended prescriptions.
Muhammad Zeeshan Ahmed +14 more
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Observations on the drug resistance of bacterial recombinants
Proceedings of the Royal Society of London. Series B - Biological Sciences, 1959Abstract Strains of Escherichia coli ‘K-12’, sensitive or resistant to chloramphenicol, proflavine or brilliant green were crossed, and the drug resistance of the recombinant strains examined. For this purpose a quantitative scale of resistance was established, so that the spectrum of the distribution among the recombinants could be ...
G W, BARTLETT, C, HINSHELWOOD
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A mechanistic perspective on targeting bacterial drug resistance with nanoparticles
Journal of Drug Targeting, 2021Bacterial infections are an important cause of mortality worldwide owing to the prevalence of drug resistant bacteria. Bacteria develop resistance against antimicrobial drugs by several mechanisms such as enzyme inactivation, reduced cell permeability, modifying target site or enzyme, enhanced efflux because of high expression of efflux pumps, biofilm ...
Khatereh, Khorsandi +4 more
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Molecular Genetics, Microbiology and Virology (Russian)
Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
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Genetic control of different pathways of drug-resistance formation in bacteria is presented. Possible molecular mechanisms of “new” genes integration into the genomes by horizontal gene transfer are discussed. This review may be valuable for physicians, veterinarians and scientific researches engaged in bacterial evolution.
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Bacterial Genotypic Drug Resistance Assays
2017The increasing emergence of antimicrobial multiresistance has significantly reduced the therapeutic options available for treating common bacterial infections. We are facing a serious worldwide health crisis but, paradoxically, this is also an exciting time since the rapid evolution of genomic technologies has facilitated the development of molecular ...
A. Huletsky, Michel G. Bergeron
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A Literature Review of Bacterial Drug Resistance
Materials Science Forum, 2020This paper summarizes the use of antibiotics and the current situation of bacterial resistance and explores the specific causes of bacterial resistance. Several commonly used and emerging detection techniques are described and compared. Finally, several measures and methods to reduce bacterial resistance are proposed.
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