Results 51 to 60 of about 604,624 (306)

Eradication Therapy - Recent Trend in Research [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2020
It is well known that Helicobacter pylori (H. pylori) can cause peptic ulcer, mucosa-associated lymphoid tissue lymphoma, atrophic gastritis, intestinal metaplasia, and ultimately, gastric cancer. Various studies have proven that H.
Heung Up Kim
doaj   +1 more source

E. coli Group 1 Capsular Polysaccharide Exportation Nanomachinary as a Plausible Antivirulence Targetin the Perspective of Emerging Antimicrobial Resistance [PDF]

, 2017
Bacteria evolving resistance against the action of multiple drugs and its ability to disseminate the multidrug resistance trait(s) across various strains of the same bacteria or different bacterial species impose serious threat to public health ...
Palur, R V, Rathinavelan, Thenmalarchelvi, Sachdeva, S, Sudhakar, K U   +3 more
core   +1 more source

Defence against bacterial drug resistance. [PDF]

BMJ, 1976
Everyone knows that acquired microbic resistance is the Achilles heel of chemotherapy. All living things can acquire some resistance to noxious agents-man to morphine, for instance. Bacteria are no exception: they can become more resistant in some degree even to ordinary germicides.
openaire   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Predicting bacterial fitness cost associated with drug resistance [PDF]

Journal of Antimicrobial Chemotherapy, 2012
It has been proposed that antimicrobial resistance could be associated with a fitness cost in bacteria, which is often determined by competition experiments between isogenic strains (wild-type and mutant). However, this conventional approach is time consuming and labour intensive.
Beining, Guo, Kamilia, Abdelraouf, Kimberly R, Ledesma, Michael, Nikolaou, Vincent H, Tam   +4 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Genome-wide identification of essential genes in the invasive Streptococcus anginosus strain

Scientific Reports
Streptococcus anginosus, part of the Streptococcus anginosus group (SAG), is a human commensal increasingly recognized as an opportunistic pathogen responsible for abscesses formation and infections, also invasive ones.
Aleksandra Kuryłek, Jan Gawor, Karolina Żuchniewicz, Robert Gromadka, Izabela Kern-Zdanowicz   +4 more
doaj   +1 more source

Sodium Benzoate is Associated with Salmonella Typhi Resistant to Chloramphenicol [PDF]

, 2016
Background: There are many factors that govern growth and resistant of Salmonella typhi. A study had reported that the use of sodium benzoate caused antibiotic resistant.
Anand, J. R. (Jay), Dewi, A. R. (Ariani), Fajar, J. K. (Jonny), Puspitasari, R. A. (Retno), Yahya, A. (Arif)   +4 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source