Results 51 to 60 of about 1,077,335 (347)

Bacterial Natural Product Drug Discovery for New Antibiotics: Strategies for Tackling the Problem of Antibiotic Resistance by Efficient Bioprospecting

Antibiotics, 2021
The problem of antibiotic resistance has become a challenge for our public health and society; it has allowed infectious diseases to re-emerge as a risk to human health.
Y. Schneider
semanticscholar   +1 more source

In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]

, 2015
The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra, Fernandez Pinar, Regina, Imperi, Francesco, LO SCIUTO, Alessandra, Ranucci, Serena, Rossi, Alice   +5 more
core   +1 more source

The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility

Frontiers in Microbiology, 2019
Urinary tracts infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is a common infectious disease. With the shortage of new antimicrobial agents, the increase in UPEC resistance to commonly used drugs, such as fluoroquinolones and β-lactams ...
Hidetada Hirakawa, Kazutomo Suzue, Kumiko Kurabayashi, Haruyoshi Tomita, Haruyoshi Tomita   +4 more
doaj   +1 more source

Common themes in antimicrobial and anticancer drug resistance

Frontiers in Microbiology, 2022
Antimicrobial and anticancer drug resistance represent two of the main global challenges for the public health, requiring immediate practical solutions.
M. Chifiriuc, Roxana Filip, M. Constantin, G. Pîrcălăbioru, C. Bleotu, L. Burlibașa, E. Ionica, N. Corcionivoschi, G. Mihăescu   +8 more
semanticscholar   +1 more source

Drug resistance, bacterial; bacterial infections; anti-bacterial agents; Streptococcus pyogenes; surgery, oral; mouth.

Journal of Oral Research, 2020
Orofacial infections are considered as one of most common infections and need rapid and adequate treatment as they affect a very delicate region and are associated with serious life-threatening complications.
Noor Abdullah Sulaiman, Sabah Abdulaziz Issa, Najwa Abdul Razzak   +2 more
doaj   +1 more source

Eucalyptus camaldulensis for combating the Multi Drug Resistance Bacterial Strains (MDRS).

Brazilian journal of biology = Revista brasleira de biologia
Antibiotic resistance in bacteria is the primary challenge for health worldwide. The widespread of food poisoning due to use of stored food items increasing day by day.
H. M. Taj, F. Zubair, N. Riaz, S. Taj, N. Amjad, A. Iqbal, R. Afzal, A. Ghaffar, S. Kiran, M. I. U. Saleemi   +9 more
semanticscholar   +1 more source

CRISPR-Cas-Based Antimicrobials: Design, Challenges, and Bacterial Mechanisms of Resistance

ACS Infectious Diseases, 2023
The emergence of antibiotic-resistant bacterial strains is a source of public health concern across the globe. As the discovery of new conventional antibiotics has stalled significantly over the past decade, there is an urgency to develop novel ...
Arianna Mayorga-Ramos, Johana Zúñiga-Miranda, Saskya E. Carrera-Pacheco, Carlos Barba-Ostria, Linda P. Guamán   +4 more
semanticscholar   +1 more source

Genomic dissection of nosocomial multiclonal-outbreak by carbapenem-resistant Pseudomonas aeruginosa strains in a tertiary children’s hospital in Japan

Journal of Global Antimicrobial Resistance
Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is an important antimicrobial-resistant bacterial pathogen. We observed an increase in the detection rate of CRPA isolates at a tertiary children’s hospital in Japan.
Akihiko Shimizu, Jun Kurushima, Koichi Tanimoto, Naoko Tomie, Yusuke Hashimoto, Takahiro Nomura, Natsuko Ota, Hidetada Hirakawa, Haruyoshi Tomita   +8 more
doaj   +1 more source

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

Nature Communications, 2018
Polymyxins remain the last line treatment for multidrug-resistant (MDR) infections. As polymyxins resistance emerges, there is an urgent need to develop effective antimicrobial agents capable of mitigating MDR.
Willy Chin, Guansheng Zhong, Qinqin Pu, Chuan Yang, Weiyang Lou, P. F. de Sessions, Balamurugan Periaswamy, Ashlynn L. Z. Lee, Zhen Chang Liang, Xin Ding, Shujun Gao, Collins Wenhan Chu, S. Bianco, C. Bao, Y. Tong, W. Fan, Min Wu, J. Hedrick, Yi Yan Yang   +18 more
semanticscholar   +1 more source

Bloodstream infections in adult patients with malignancy, epidemiology, microbiology, and risk factors associated with mortality and multi-drug resistance

BMC Infectious Diseases, 2021
Background This study aimed to investigate the epidemiology, microbiology, and risk factors associated with mortality and multi-drug resistance bacterial bloodstream infections (BSIs) among adult cancer patients in Shiraz, Iran.
Ali Amanati, Sarvin Sajedianfard, Somayeh Khajeh, Shabnam Ghasempour, Salma Mehrangiz, S. Nematolahi, Zahra Shahhosein   +6 more
semanticscholar   +1 more source