Results 111 to 120 of about 4,538,104 (325)

The Plant‐to‐Plant Circular Strategy: Coupling Photodegradation and Phytoremediation With Plant‐Based Nanomaterials for Plastic Degradation

Advanced Science, EarlyView.
Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu, Lena Ciric, Yuheng Wang, Ziru Pei, Manpreet Bhatti   +4 more
wiley   +1 more source

Epigenetics as a mechanism driving polygenic clinical drug resistance [PDF]

, 2006
Aberrant methylation of CpG islands located at or near gene promoters is associated with inactivation of gene expression during tumour development.
Glasspool, R.M., Teodoridis, JM, Glasspool, RM, Teodoridis, J.M., Brown, R, R M Glasspool, Brown, R., J M Teodoridis, R Brown   +8 more
core   +1 more source

Paraborg: Paramedic Cyborg Insects for In Situ Emergency Drug‐Delivery

Advanced Science, EarlyView.
This work introduces Paraborg, a human‐supervised paramedic cyborg‐insect platform that combines controllable locomotion, onboard imaging, and an auto‐injection mechanism for in situ drug‐delivery. By demonstrating reliable navigation, target stabilization, injector launch, and multi‐insect teamwork, the study extends cyborg insects from survivor ...
H. Nhan Le, P. Thien Phan, Lachlan Fitzgerald, P. Ross McAree, T. Nho Do, T. Thang Vo‐Doan   +5 more
wiley   +1 more source

Drug resistance mutations in drug-naive HIV type 1 subtype C-infected individuals from rural Malawi. [PDF]

, 2010
In this preliminary study we show that in 2008, 3 years after antiretroviral therapy was introduced into the Karonga District, Malawi, a greater than expected number of drug-naive individuals have been infected with HIV-1 subtype C virus harboring major ...
Grace P. McCormack, Emmanuel Banda, Judith R. Glynn, Bansode, Vijay, McCormack, Grace P., Glynn, Judith R., Neil French, French, Neil, Glynn, Judith R, Zuzanna J. Drebert, Banda, Emmanuel, Drebert, Zuzanna J., Molesworth, Anna, Vijay Bansode, Travers, Simon AA, Amelia Crampin, Drebert, Zuzanna, McCormack, Grace P, Crampin, Amelia, Anna Molesworth, Drebert, Zuzanna J, Simon A.A. Travers, Travers, Simon A A, Travers, Simon A.A., Ngwira, Bagrey, Bagrey Ngwira   +25 more
core   +1 more source

Candida antifungal drug resistance in sub-Saharan African populations: A systematic review [version 2; referees: 2 approved]

F1000Research, 2017
Background: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV co-infection.
Charlene Wilma Joyce Africa, Pedro Miguel dos Santos Abrantes   +1 more
doaj   +1 more source

Insights into the role of sterol metabolism in antifungal drug resistance: a mini-review

Frontiers in Microbiology
Sterols are essential for eukaryotic cells and are crucial in cellular membranes’ structure, function, fluidity, permeability, adaptability to environmental stressors, and host-pathogen interactions. Fungal sterol, such as ergosterol metabolism, involves
Sunita Tanwar, Sapna Kalra, V. Bari
semanticscholar   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Post-translational modifications in drug resistance

Resistance to antitumor drugs, antimicrobial drugs, and antiviral drugs severely limits treatment effectiveness and cure rate of diseases. Protein post-translational modifications (PTMs) represented by glycosylation, ubiquitination, SUMOylation ...
Zhang, Cheng, Miao, Chenggui, Zhou, Xinyue, Chen, Zhe Sheng, Huang, Yurong, Wang, Bing, Song, Yingqiu, Feng, Yibin, Wu, Peng, Wang, Xiao   +9 more
core   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Pyrethroid resistance in Anopheles gambiae leads to increased susceptibility to the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana [PDF]

, 2010
Background Entomopathogenic fungi are being investigated as a new mosquito control tool because insecticide resistance is preventing successful mosquito control in many countries, and new methods are required that can target insecticide-resistant malaria
Knols, B.G.J., Bart GJ Knols, Howard, Annabel F. V., Koenraadt, C.J.M., Annabel FV Howard, Knols Bart GJ, Farenhorst, Marit, Knols, Bart G. J., Takken, Willem, Takken Willem, Howard Annabel FV, Howard, A.F.V., Constantianus JM Koenraadt, Koenraadt, Constantianus J. M., Farenhorst, M., Marit Farenhorst, Takken, W., Koenraadt Constantianus JM, Willem Takken, Farenhorst Marit   +19 more
core   +2 more sources