Results 91 to 100 of about 4,538,104 (325)
Indian Journal of Community Medicine, 2019 Background: It is well documented in the literature that fungal infections are common in diabetic foot ulcers (DFUs). This has led to an overuse of antifungal agents, namely fluconazole, with a consequent risk of emergence of resistance to this drug ...
Chankramath S Arun +5 more
doaj +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2023 Introduction. Malassezia is a lipophilic and lipid-dependent yeast genus belonging to the skin microbiota of humans and other animals. However, due to dysbiosis processes or other factors in the host, this yeast can cause different pathologies, ranging ...
Kevin Ehemann +2 more
doaj +1 more source
High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency
Advanced Science, EarlyView.ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan +11 more
wiley +1 more source
Transferable drug resistance plasmids in fish-pathogenic bacteria [PDF]
, 2000 Chemotherapeutic agents have been developed for treating bacterial infections and have been widely used for cultured fish for the last 30 years in Japan.
Aoki, Takashi
core +1 more source
VIM-1, VIM-2, and GES-5 Carbapenemases Among Pseudomonas aeruginosa Isolates at a Tertiary Hospital in Istanbul, Turkey. [PDF]
, 2017 Worldwide increase in carbapenem resistance and transferable carbapenemases are significant challenges in treatment of Pseudomonas aeruginosa infections. In this study, investigation of carbapenemase production in carbapenem-resistant P.
Otlu, Barış +4 more
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Genetic and genomic architecture of the evolution of resistance to antifungal drug combinations. [PDF]
PLoS Genetics, 2013 The evolution of drug resistance in fungal pathogens compromises the efficacy of the limited number of antifungal drugs. Drug combinations have emerged as a powerful strategy to enhance antifungal efficacy and abrogate drug resistance, but the impact on ...
Jessica A Hill +4 more
doaj +1 more source
Drug resistance and tolerance in fungi
Nature Reviews Microbiology, 2020 Systemic fungal infections pose a serious clinical problem. Treatment options are limited, and antifungal drug resistance is increasing. In addition, a substantial proportion of patients do not respond to therapy despite being infected with fungi that ...
J. Berman, Damian J. Krysan
semanticscholar +1 more source
Advanced Science, EarlyView.Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su +7 more
wiley +1 more source
Nanoemulsion as an Effective Treatment against Human-Pathogenic Fungi
mSphere, 2019 Infections triggered by pathogenic fungi cause a serious threat to the public health care system. In particular, an increase of antifungal drug-resistant fungi has resulted in difficulty in treatment.
Alexis Garcia +6 more
doaj +1 more source
PLoS Pathogens, 2023 Fungal pathogens overcome antifungal drug therapy by classic resistance mechanisms, such as increased efflux or changes to the drug target. However, even when a fungal strain is susceptible, trailing or persistent microbial growth in the presence of an ...
Ka Pui Sharon Yau +7 more
doaj +1 more source