Results 81 to 90 of about 4,538,104 (325)

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis

PLoS Genetics, 2016
Fungal pathogens have evolved diverse strategies to sense host-relevant cues and coordinate cellular responses, which enable virulence and drug resistance.
Elizabeth J. Polvi, A. Averette, Soo-Chan Lee, Taeyup Kim, Yong-Sun Bahn, Amanda O. Veri, Nicole Robbins, J. Heitman, L. Cowen   +8 more
semanticscholar   +1 more source

Nature‐Derived Chitosan Biopolymer: A Promising Candidate for Sustainable Electronics

Advanced Materials Technologies, EarlyView.
In the creation of environmentally friendly devices, nature‐derived chitosan biopolymer is a promising contender for sustainable electronic research. It can be utilized to create more ecologically friendly scalable gadgets and has a variety of uses in different active layers of electronics.
Joshua McDonald, Ali Nawaz, Amandeep Singh, Prashant Sonar   +3 more
wiley   +1 more source

_M. tuberculosis_ interactome analysis unravels potential pathways to drug resistance [PDF]

, 2008
Drug resistance is a major problem for combating tuberculosis. Lack of understanding of how resistance emerges in bacteria upon drug treatment limits our ability to counter resistance.
Nagasuma Chandra, Karthik Raman
core  

Exploiting the behaviour of wild malaria vectors to achieve high infection with fungal biocontrol agents [PDF]

, 2012
Background Control of mosquitoes that transmit malaria has been the mainstay in the fight against the disease, but alternative methods are required in view of emerging insecticide resistance.
Kirby, Matthew J, Mpingwa, Monica W, Mpingwa, M W, Russell, T, Koenraadt, C J M, Koenraadt, Constantianus J M, Lyimo, Issa N, Lyimo, I.N., Mpingwa, M. W., Mpingwa Monica W, Lwetoijera, Dickson W., Nchimbi, Nuru, Takken, W., Mpingwa, M.W., Mnyone, Ladslaus L, Hancock Penelope A, Mnyone, L L, Koenraadt, C.J.M., Hancock, P.A., Nchimbi, N, Hancock, Penelope A, Takken, Willem, Lwetoijera, D. W., Nuru Nchimbi, Koenraadt, C. J. M., Hancock, P A, Koenraadt, Constantianus JM, Lyimo Issa N, Russell Tanya L, Lwetoijera Dickson W, Issa N Lyimo, Koenraadt Constantianus JM, Nchimbi Nuru, Kirby, M.J., Willem Takken, Mnyone, L. L., Hancock, Penelope A., Kirby, Matthew J., Matthew J Kirby, Lwetoijera, D W, Mnyone, Ladslaus L., Kirby Matthew J, Mpingwa, Monica W., Lwetoijera, D.W., Hancock, P. A., Constantianus JM Koenraadt, Koenraadt, Constantianus J.M., Koenraadt, Constantianus J. M., Takken, W, Ladslaus L Mnyone, Russell, T. L., Lyimo, Issa N., Tanya L Russell, Mnyone Ladslaus L, Dickson W Lwetoijera, Lwetoijera, Dickson W, Kirby, M. J., Penelope A Hancock, Takken Willem, Lyimo, I N, Lyimo, I. N., Monica W Mpingwa, Kirby, M J, Mnyone, L.L., Nchimbi, N., Mnyone, Ladslaus, Russell, Tanya L, Russell, T.L., Russell, Tanya L.   +68 more
core   +1 more source

Recent gene selection and drug resistance underscore clinical adaptation across Candida species

Nature Microbiology
Phylogenetics and convergence-based genome-wide association studies were used to analyse genomic variants across approximately 2,000 isolates from six Candida species to reveal how Candida fungal pathogens adapt to drugs and clinical environments ...
Miquel Àngel Schikora-Tamarit, Toni Gabaldón   +1 more
semanticscholar   +1 more source

Drug resistance in Candida albicans isolates and related changes in the structural domain of Mdr1 protein.

Journal of Infection and Public Health, 2021
BACKGROUND The increasing azole drug resistance in fungal pathogens poses a pressing threat to global health care. The coexistence of drug-resistant Candida albicans with tuberculosis patients and the failure of several drugs to treat C.
P. Dhasarathan, M. Alsalhi, S. Devanesan, Jeeva Subbiah, A. J. A. Ranjitsingh, Mohammed Binsalah, Akram A. Alfuraydi   +6 more
semanticscholar   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Flipping and other astonishing transporter dance moves in fungal drug resistance

BioEssays, 2022
AbstractIn all domains of life, transmembrane proteins from the ATP‐binding cassette (ABC) transporter family drive the translocation of diverse substances across lipid bilayers. In pathogenic fungi, the ABC transporters of the pleiotropic drug resistance (PDR) subfamily confer antibiotic resistance and so are of interest as therapeutic targets.
Raschka, Stefanie L, Harris, Andrzej, Luisi, Ben F, Schmitt, Lutz   +3 more
openaire   +2 more sources

Fungal plasticity drives adaptation and survival across pathogenic and free-living contexts

Discover Life
Fungal dynamicity drives rapid adaptation to environmental changes, contributing to the development of antifungal resistance, phenotypic switching, and the emergence of opportunistic pathogenicity.
Tedros Gebrezgiabhier Gebreyesus
doaj   +1 more source