Results 1 to 10 of about 310,675 (185)

Multimodal Role of Amino Acids in Microbial Control and Drug Development [PDF]

Antibiotics, 2020
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms including those in the microbial world. They are utilised as nutrients and control many biological functions in microorganisms such as cell division, cell wall formation,
Muhammad Idrees, Afzal R. Mohammad, Nazira Karodia, Ayesha Rahman   +3 more
doaj   +4 more sources

Modeling microbial drug-resistance: from mathematics to pharmacoeconomics

Фармакоэкономика, 2018
Complicated intra-abdominal infection (IAI) requires increased health care expenditures and additional resources to compensate for an ineffective starting therapy.Aim. To select the economically optimal algorithm for using antimicrobial agents (AMA) that
Yu. M. Gomon, M. A. Arepyeva, Yu. E. Balykina, A. S. Kolbin, A. A. Kurylev, M. A. Proskurin, S. V. Sidorenko   +6 more
doaj   +4 more sources

Enhanced diagnosis of multi-drug-resistant microbes using group association modeling and machine learning [PDF]

Nature Communications
New solutions are needed to detect genotype-phenotype associations involved in microbial drug resistance. Herein, we describe a Group Association Model (GAM) that accurately identifies genetic variants linked to drug resistance and mitigates false ...
Julian G. Saliba, Wenshu Zheng, Qingbo Shu, Liqiang Li, Chi Wu, Yi Xie, Christopher J. Lyon, Jiuxin Qu, Hairong Huang, Binwu Ying, Tony Ye Hu   +10 more
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An exploration of the ocular mysteries linking nanoparticles to the patho-therapeutic effects against keratitis [PDF]

Journal of Nanobiotechnology
Microbial keratitis, a sight-threatening corneal infection, remains a significant global health concern. Conventional therapies using antimicrobial agents often suffers from limitations such as poor drug penetration, side effects, and occurrence of drug ...
Siying Qu, Shuihua Zheng, Sibtain Muhammad, Liang Huang, Bing Guo   +4 more
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Biocide-Resistant Escherichia coli ST540 Co-Harboring ESBL, dfrA14 Confers QnrS-Dependent Plasmid-Mediated Quinolone Resistance

Antibiotics, 2022
Emerging sequence types of pathogenic bacteria have a dual ability to acquire resistance islands/determinants, and remain renitent towards disinfection practices; therefore, they are considered “critical risk factors” that contribute significantly to the
Srinivasan Vijaya Bharathi, Govindan Rajamohan   +1 more
doaj   +1 more source

Phenotypic Characterization and Heterogeneity among Modern Clinical Isolates of Acinetobacter baumannii

Microbiology Spectrum, 2023
Acinetobacter baumannii is an opportunistic pathogenic bacterium prioritized by WHO and CDC because of its increasing antibiotic resistance. Heterogeneity among strains represents the hallmark of A. baumannii bacteria.
Adam Valcek, Chantal Philippe, Clémence Whiteway, Etienne Robino, Kristina Nesporova, Mona Bové, Tom Coenye, Tim De Pooter, Wouter De Coster, Mojca Strazisar, Charles Van der Henst   +10 more
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Antimicrobial Activity of a Repurposed Harmine-Derived Compound on Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates

Frontiers in Cellular and Infection Microbiology, 2022
ObjectivesThe spread of antibiotic resistant bacteria is an important threat for human health. Acinetobacter baumannii bacteria impose such a major issue, as multidrug- to pandrug-resistant strains have been isolated, rendering some infections ...
Anke Breine, Anke Breine, Mégane Van Gysel, Mathias Elsocht, Clémence Whiteway, Clémence Whiteway, Chantal Philippe, Théo Quinet, Théo Quinet, Adam Valcek, Adam Valcek, Johan Wouters, Steven Ballet, Charles Van der Henst, Charles Van der Henst   +14 more
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Geraniol-a potential alternative to antibiotics for bovine mastitis treatment without disturbing the host microbial community or causing drug residues and resistance

Frontiers in Cellular and Infection Microbiology, 2023
Mastitis is one of the most prevalent diseases of dairy cows. Currently, mastitis treatment in dairy cows is mainly based on antibiotics. However, the use of antibiotics causes adverse effects, including drug resistance, drug residues, host-microbiome ...
Wei Guo, Wei Guo, Min Qiu, Zhonghui Pu, Zhonghui Pu, Nana Long, Min Yang, Min Yang, Ke Ren, Ke Ren, Ruihong Ning, Siyuan Zhang, Siyuan Zhang, Fu Peng, Fenghui Sun, Min Dai, Min Dai   +16 more
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Hybrid Azine Derivatives: A Useful Approach for Antimicrobial Therapy

Pharmaceutics, 2022
Nowadays, infectious diseases caused by microorganisms are a major threat to human health, mostly because of drug resistance, multi-drug resistance and extensive-drug-resistance phenomena to microbial pathogens.
Dorina Amariucai-Mantu, Violeta Mangalagiu, Iustinian Bejan, Aculina Aricu, Ionel I. Mangalagiu   +4 more
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Antimicrobial resistance and genomic characterization of Salmonella enterica isolates from chicken meat

Frontiers in Microbiology, 2023
This study investigated genotypic and phenotypic antimicrobial resistance profiles, phylogenic relatedness, plasmid and virulence composition of 39 Salmonella enterica strains isolated from chicken meat samples using whole genome sequencing (WGS ...
Khaloud O. Alzahrani, Fahad M. AL-Reshoodi, Elaf A. Alshdokhi, Ashwaq S. Alhamed, Meshari A. Al Hadlaq, Mohammed I. Mujallad, Lenah E. Mukhtar, Amani T. Alsufyani, Abdullah A. Alajlan, Malfi S. Al Rashidy, Mashan J. Al Dawsari, Saleh I. Al-Akeel, Meshari H. AL-Harthi, Abdulaziz M. Al Manee, Abdulaziz M. Al Manee, Majed F. Alghoribi, Majed F. Alghoribi, Suliman M. Alajel   +17 more
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