Results 261 to 270 of about 692,751 (314)

Drug repurposing to overcome microbial resistance

Drug Discovery Today, 2022
Infections are a growing global threat, and the number of resistant species of microbial pathogens is alarming. However, the rapid development of cross-resistant or multidrug-resistant strains and the development of so-called 'superbugs' are in stark contrast to the number of newly launched anti-infectives on the market. In this review, I summarize the
J. JampĂ­lek
openaire   +3 more sources

Quorum sensing and microbial drug resistance.

Yi chuan = Hereditas, 2016
Microbial drug resistance has become a serious problem of global concern, and the evolution and regulatory mechanisms of microbial drug resistance has become a hotspot of research in recent years. Recent studies showed that certain microbial resistance mechanisms are regulated by quorum sensing system.
Lian-Hui Zhang   +5 more
openaire   +4 more sources

A modified fluctuation test for elucidating drug resistance in microbial and cancer cells

bioRxiv, 2020
Clonal populations of microbial and cancer cells are often driven into a drug-tolerant persister state in response to drug therapy, and these persisters can subsequently adapt to the new drug environment via genetic and epigenetic mechanisms.
Pavol Bokes, Abhyudai Singh
semanticscholar   +1 more source

Microbial Drug Resistance

JAMA: The Journal of the American Medical Association, 1997
The stated intention of Microbial Drug Resistance is to be "an international journal that provides a multi-disciplinary forum for peer reviewed original papers as well as topical reviews and special reports." It focuses primarily upon "the emergence and spread of antibiotic-resistant microbial pathogens and resistance genes, and the challenges they ...
Anne M. Pascarelli, William W. McCloskey
openaire   +2 more sources

Microbial and viral drug resistance mechanisms

Trends in Microbiology, 2002
Microorganisms and viruses have developed numerous resistance mechanisms that enable them to evade the effect of antimicrobials and antivirals. As a result, many have become resistant to almost every available means of treatment. This problem, although not new, is becoming increasingly acute and it is now clear that a fundamental understanding of the ...
Adrian R. Walmsley   +2 more
openaire   +2 more sources

Biocides, drug resistance and microbial evolution

Current Opinion in Microbiology, 2001
Antimicrobial biocides are widely used in critical human health situations in which rigorous infection control is needed. Increasingly, biocidal agents are being marketed for home use, although there is little evidence that they significantly improve home hygiene. Biocide resistance mechanisms share many themes with antibiotic resistance mechanisms.
David G. White, Patrick F. McDermott
openaire   +2 more sources

Home - About - Disclaimer - Privacy