New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infection: report of a survivor
: New Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right ...
Fabiana Schuelter-Trevisol +7 more
doaj +1 more source
Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance [PDF]
BACKGROUND:The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Bu, Ji-Hye +12 more
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
The effect of combined sewer overflows on the abundance of antibiotic resistance genes and bacteria in the James River [PDF]
Antibiotic resistance is a major threat to human health. Clinical situations are the main focus for antibiotic resistance research, but understanding the spread of resistance in the environment is also vital.
Levengood, Enjolie
core +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Steps to address anti-microbial drug resistance in today’s drug discovery [PDF]
There is no doubt that antimicrobial resistance (AMR) is one of the greatest health risks to emerge in the 21st century.
openaire +2 more sources
Compounding Effects of Climate Warming and Antibiotic Resistance. [PDF]
Bacteria have evolved diverse mechanisms to survive environments with antibiotics. Temperature is both a key factor that affects the survival of bacteria in the presence of antibiotics and an environmental trait that is drastically increasing due to ...
Cruz-Loya, Mauricio +4 more
core +1 more source
Impact of the gut microbiota on inflammation, obesity, and metabolic disease [PDF]
The human gut harbors more than 100 trillion microbial cells, which have an essential role in human metabolic regulation via their symbiotic interactions with the host.
Boulangé, CL +4 more
core +1 more source
Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo +3 more
wiley +1 more source
An evaluation of methods to assess the effect of antimicrobial residues on the human gut flora [PDF]
1. Barrier effect. Relevant models should include an anaerobic dominant flora that antagonizes minor bacterial populations such as drug resistant E. coli. 2. Anaerobes vs. aerobes.
Corpet, Denis E.
core +2 more sources

