Results 261 to 270 of about 2,071,500 (370)

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Prevalence of <i>Acinetobacter baumannii</i> Multidrug Resistance in University Hospital Environment. [PDF]

Antibiotics (Basel)
Foglia F, Ambrosino A, Bashir S, Finamore E, Zannella C, Donnarumma G, De Filippis A, Galdiero M.   +7 more
europepmc   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Decoding resistance to immune checkpoint inhibitors in non-small cell lung cancer: a comprehensive analysis of plasma proteomics and therapeutic implications. [PDF]

J Immunother Cancer
Harel M, Dahan N, Lahav C, Jacob E, Elon Y, Puzanov I, Kelly RJ, Shaked Y, Leibowitz R, Carbone DP, Gandara DR, Dicker AP.   +11 more
europepmc   +1 more source

Ageism in Rheumatology: the Healthcare Professional's Perspective

Arthritis Care &Research, Accepted Article.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the healthcare professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact ...
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source

Inefficiency Rates of Biological Immunosuppressive Induction Agents Used in Organ Transplantation: A Pharmacovigilance Study. [PDF]

J Clin Med
Butuca A, Stoicescu L, Popa ML, Dobrea CM, Muntean A, Morgovan C, Pienar C, Gligor FG, Ghibu S, Popa Ilie IR, Frum A.   +10 more
europepmc   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

Nanotechnology in Hematology: Enhancing Therapeutic Efficacy With Nanoparticles. [PDF]

Health Sci Rep
Fard NT, Khademi M, Salahi-Niri A, Esmaeili S.   +3 more
europepmc   +1 more source

Herbal Formula Yi‐Fei‐Jie‐Du‐Tang Regulates Epithelial‐Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A‐Mediated Ferroptosis

Advanced Biology, Volume 9, Issue 3, March 2025.
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang, Die Yang, Chengjia Yuan, Yang Wu, Qingying Wang, Yongjian Wu, Xiaochun Zhang   +6 more
wiley   +1 more source

*Mechanisms of circular RNA in drug resistance of lung cancer: therapeutic targets, biomarkers, and future research directions. [PDF]

Discov Oncol
Tao X, Ke X, Xu G.
europepmc   +1 more source