Microbiology Research, 2016 Due to the increasing prevalence of infections caused by resistant bacteria and especially multiple drug resistance Enterobacteriaceae, availability of alternative effective antibiotics is restricted.
Fatemeh Yeganeh Sefidan +2 more
doaj +1 more source
Draft Genome Sequences of Antibiotic-Resistant Commensal Escherichia coli [PDF]
, 2014 Antimicrobial resistance is a significant public health issue. We report here the draft genome sequences of three drug-resistant strains of commensal Escherichia coli isolated from a single healthy college student.
Garrett, Meghan +2 more
core +2 more sources
Tyrosol induces multiple drug resistance in yeast Saccharomyces cerevisiae
Frontiers in Microbiology, 2023 In yeast, multiple (pleiotropic) drug resistance (MDR) transporters efflux xenobiotics from the cytoplasm to the environment. Additionally, upon the accumulation of xenobiotics in the cells, MDR genes are induced.
Elizaveta O. Noskova +5 more
doaj +1 more source
Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]
, 2015 Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph +1 more
core +1 more source
Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs. [PDF]
, 2007 Parasite drug resistance is partly conferred by single-nucleotide polymorphisms (SNPs), and monitoring them has been proposed as an alternative to monitoring drug resistance.
Beck, Hans-Peter +13 more
core +2 more sources
Biomédica: revista del Instituto Nacional de Salud, 2019 Introduction: The use of antibiotics in humans, animal husbandry and veterinary activities induces selective pressure leading to the colonization and infection by resistant strains.
Verônica Dias Gonçalves +10 more
doaj +1 more source
Insulin resistance in drug naive patients with multiple sclerosis [PDF]
Vojnosanitetski Pregled, 2017 Background/Aim. Due to the fact that there is a relatively small number of data related to systemic insulin abnormalities in the multiple sclerosis (MS), the main objective of our study was to determine whether a dysbalance of glucose and ...
Kostić Smiljana +5 more
doaj +1 more source
Overcoming multiple drug resistance mechanisms in medulloblastoma [PDF]
, 2014 Introduction: Medulloblastoma (MB) is the most common malignant paediatric brain tumour. Recurrence and progression of disease occurs in 15-20% of standard risk and 30-40% of high risk patients.
Andrey Korshunov +9 more
core +1 more source
Targeting Drug Chemo-Resistance in Cancer Using Natural Products
Biomedicines, 2021 Cancer is one of the leading causes of death globally. The development of drug resistance is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms to reduce the therapeutic effects of anticancer drugs, thereby causing
Wamidh H. Talib +4 more
doaj +1 more source
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]
, 2017 Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David +13 more
core +2 more sources