Results 31 to 40 of about 638,721 (253)
Xiehe Yixue Zazhi, 2023 Objective To study the resistance of Helicobacter pylori(Hp) isolated from Peking University People's Hospital to commonly used antibiotics, in order to provide basis for clinical rational drug use.
ZHANG Feifei +7 more
doaj +1 more source
Epigenetic Regulation of Antifungal Drug Resistance
Journal of Fungi, 2022 In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra +3 more
doaj +1 more source
m6A Modification in Non-Coding RNA: The Role in Cancer Drug Resistance
Frontiers in Oncology, 2021 Cancer drug resistance has always been a major difficulty in cancer therapy. In the face of drug pressure, resistant cancer cells show complex molecular mechanisms including epigenetic changes to maintain survival. Studies prove that cancer cells exhibit
Chen Chen +9 more
doaj +1 more source
The emergence of resistance to the benzimidazole anthlemintics in parasitic nematodes of livestock is characterised by multiple independent hard and soft selective sweeps [PDF]
, 2015 Anthelmintic resistance is a major problem for the control of parasitic nematodes of livestock and of growing concern for human parasite control. However, there is little understanding of how resistance arises and spreads or of the “genetic signature” of
Bartley, Yvonne +7 more
core +3 more sources
Lijecnicki vjesnik, 1994 The multidrug-resistance (MDR) phenotype expressed in mammalian cell lines is complex. A cell selected with a single agent can acquire cross-resistance to a remarkably wide range of compounds which have no structural or functional similarities. The basis for cross-resistance seems to be a decreased net cellular accumulation of the drugs involved, and ...
C R, Leveille, A S, Moore
openaire +3 more sources
Туберкулез и болезни лёгких, 2023 The objective: to evaluate the efficacy and safety of bedaquiline in new chemotherapy regimens in HIV-positive tuberculosis patients.Subjects and Methods.
O. E. Russkikh +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Peroxiredoxin III : a candidate for drug resistance to chemotherapy : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2008 The development of drug resistance to chemotherapeutic drugs is a serious obstacle in the successful treatment of cancer. New cancer drugs are continually being developed with the goal of increasing the effectiveness of chemotherapy.
Aalderink, Miranda
core
In vitro development of chemotherapy and targeted therapy drug-resistant cancer cell lines: a practical guide with case studies [PDF]
, 2014 The development of a drug-resistant cell line can take from 3 to 18 months. However, little is published on the methodology of this development process. This article will discuss key decisions to be made prior to starting resistant cell line development;
Breen, Laura +7 more
core +2 more sources
Cancer Communications, 2021 Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises from the interaction of multiple factors including tobacco, alcohol consumption, and betel quid.
Xiang Meng +7 more
doaj +1 more source