Results 11 to 20 of about 7,297 (168)

Fosfomycin, a therapeutic option for infections produced by multiple drug-resistant Enterobacteriaceae

Microbiology Research, 2016
Due to the increasing prevalence of infections caused by resistant bacteria and especially multiple drug resistance Enterobacteriaceae, availability of alternative effective antibiotics is restricted.
Fatemeh Yeganeh Sefidan, Robab Azargun, Reza Ghotaslou   +2 more
doaj   +1 more source

Detection of multidrug-resistant Enterobacteriaceae isolated from river waters flowing to the Guanabara Bay and from clinical samples of hospitals in Rio de Janeiro, Brazil

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: The use of antibiotics in humans, animal husbandry and veterinary activities induces selective pressure leading to the colonization and infection by resistant strains.
Verônica Dias Gonçalves, Frederico Meirelles-Pereira, Márcio Cataldo, Bianca de Oliveira Fonseca, Barbara Araujo Nogueira, Julianna Giordano Botelho Olivella, Francisco de Assis Esteves, Ana Luiza Mattos-Guaraldi, Arnaldo Feitosa Braga de Andrade, Alexandre Ribeiro Bello, José Augusto Adler Pereira   +10 more
doaj   +1 more source

Insulin resistance in drug naive patients with multiple sclerosis [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Due to the fact that there is a relatively small number of data related to systemic insulin abnormalities in the multiple sclerosis (MS), the main objective of our study was to determine whether a dysbalance of glucose and ...
Kostić Smiljana, Kolić Ivana, Raičević Ranko, Stojanović Zvezdana, Kostić Dejan, Dinčić Evica   +5 more
doaj   +1 more source

Targeting Drug Chemo-Resistance in Cancer Using Natural Products

Biomedicines, 2021
Cancer is one of the leading causes of death globally. The development of drug resistance is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms to reduce the therapeutic effects of anticancer drugs, thereby causing
Wamidh H. Talib, Ahmad Riyad Alsayed, Muna Barakat, May Ibrahim Abu-Taha, Asma Ismail Mahmod   +4 more
doaj   +1 more source

Clinical Resistance of Helicobacter pylori and Its Trend: A 10-year Data Analysis at Peking University People's Hospital

Xiehe Yixue Zazhi, 2023
Objective  To study the resistance of Helicobacter pylori(Hp) isolated from Peking University People's Hospital to commonly used antibiotics, in order to provide basis for clinical rational drug use.
ZHANG Feifei, WANG Qi, LI Shuguang, WANG Zhanwei, LIANG Xinyue, MENG Han, YANG Shuo, WANG Hui   +7 more
doaj   +1 more source

Selinexor Overcomes Hypoxia-Induced Drug Resistance in Multiple Myeloma

Translational Oncology, 2017
Increased levels of the nuclear export protein, exportin 1 (XPO1), were demonstrated in multiple myeloma (MM) patients. Targeting XPO1 with selinexor (the selective inhibitor of nuclear export; SINE compound KPT-330) demonstrates broad antitumor activity
Barbara Muz, Feda Azab, Pilar de la Puente, Yosef Landesman, Abdel Kareem Azab   +4 more
doaj   +1 more source

Epigenetic Regulation of Antifungal Drug Resistance

Journal of Fungi, 2022
In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra, Mayur Raney, Aditi Pareek, Rupinder Kaur   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Efficacy and safety of bedaquiline in treatment regimens in patients TB/HV co-infection in the Udmurt Republic

Туберкулез и болезни лёгких, 2023
The objective: to evaluate the efficacy and safety of bedaquiline in new chemotherapy regimens in HIV-positive tuberculosis patients.Subjects and Methods.
O. E. Russkikh, E. V. Savintseva, D. A. Kudlay, Zh. I. Krivosheeva   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source