Results 31 to 40 of about 4,670,790 (255)

Phenotypic drug-susceptibility profiles and genetic analysis based on whole-genome sequencing of Mycobacterium avium complex isolates in Thailand.

PLoS ONE, 2023
Mycobacterium avium complex (MAC) infections are a significant clinical challenge. Determining drug-susceptibility profiles and the genetic basis of drug resistance is crucial for guiding effective treatment strategies.
Auttawit Sirichoat, Orawee Kaewprasert, Yothin Hinwan, Kiatichai Faksri   +3 more
doaj   +1 more source

High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581. [PDF]

, 2009
BACKGROUND: Sulphadoxine-pyrimethamine (SP) a widely used treatment for uncomplicated malaria and recommended for intermittent preventive treatment of malaria in pregnancy, is being investigated for intermittent preventive treatment of malaria in infants
Gesase Samwel, Daniel Chandramohan, Mosha Jacklin F., Mandia, Victor, Joho, Angel, Victor Mandia, Martha Lemnge, Greenwood, Brian, Samwel Gesase, Gesase, Samwel, Chandramohan Daniel, Mosha Frank W., Savael, Zacharia, Ord, Rosalynn, Roper, Cally, Angel Joho, Madebe, Rashid, Greenwood Brian, Hashim Ramadhan, Frank W. Mosha, Mrema Hedwiga, Inbarani Naidoo, Chandramohan, Daniel, Zacharia Savael, Mapunda Ephraim, Mosha, Frank W, Lemnge Martha, Madebe Rashid, Rosalynn Ord, Mapunda, Ephraim, Ephraim Mapunda, Roly D Gosling, Naidoo Inbarani, Frank W Mosha, Hashim, Ramadhan, Cally Roper, Mandia Victor, Gosling, Roly D, Victor M, Jacklin F. Mosha, Gosling Roly D., Lemnge, Martha, Ord Rosalynn, Hedwiga Mrema, Brian Greenwood, Mrema, Hedwiga, Roly D. Gosling, Roper Cally, Jacklin F Mosha, Ramadhan Hashim, Rashid Madebe, Mosha, Jacklin F, Naidoo, Inbarani, Savael Zacharia, Joho Angel   +54 more
core   +2 more sources

Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration [PDF]

, 2005
Background The genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral treatment is expanded to regions of the world where diverse non-subtype-B viruses predominate.Methods and ...
Wynhoven, B, Cane, P, Holguin, A, Pedro Cahn, Maria Belen Bouzas, Africa Holguin, Luis F Brigido, Sirivichayakul, S, Anne-Mieke Vandamme, Camacho, R, Efron, B, Koya Ariyoshi, Grossman, Z, Robert W Shafer, Shafer, RW, Bouzas, MB, Brian Wynhoven, Ricardo Camacho, Jonathan N Weber, Harrigan, PR, Ariyoshi, K, Ana Patricia Carvalho, Rosangela Rodrigues, Rudich, H, Candice Pillay, Soares, MA, Katzenstein, DA, Vandamme, AM, Clarke, J, Lynn Morris, Snoeck, J, Soriano, V, Rodrigues, R, Brigido, LF, Wataru Sugiura, Praphan Phanuphak, Kantor, R, Sugiura, W, John Clarke, Jonathan M Schapiro, Rami Kantor, David A Katzenstein, Carvalho, AP, P Richard Harrigan, Patricia Cane, Phanuphak, P, Brad Efron, Pillay, D, Pillay, C, Sunee Sirivichayakul, Joke Snoeck, Cahn, P, Hagit Rudich, Schapiro, JM, Morris, L, Zehava Grossman, Amilcar Tanuri, Tanuri, A, Weber, JN, Vincent Soriano, Deenan Pillay, Marcelo A Soares   +61 more
core   +2 more sources

Challenges of drug resistance in the management of pancreatic cancer [PDF]

, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Naomi Walsh, Martin Clynes, Rizwan Sheikh, Sheikh, Rizwan, O'Connor, Robert A., Robert O’Connor, Ray McDermott, O'Connor, Robert, Clynes, Martin, Walsh, Naomi, McDermott, Ray   +10 more
core   +1 more source

Antiretroviral resistance in HIV-1 patients at a tertiary medical institute in Saudi Arabia: a retrospective study and analysis

BMC Infectious Diseases, 2018
Background Since the early 90’s antiretroviral drugs have been available at King Faisal Specialist Hospital and Research Centre (KFSH&RC), a referral hospital in Riyadh, Saudi Arabia, for the treatment of both adults and children infected with HIV-1 ...
Maha Al-Mozaini, Tahani Alrahbeni, Reem Al-Mograbi, Abdulrahman Alrajhi   +3 more
doaj   +1 more source

Immune Escape and Drug Resistance Mutations in Patients with Hepatitis B Virus Infection: Clinical and Epidemiological Implications. [PDF]

Life (Basel)
De Francesco MA, Gargiulo F, Dello Iaco F, Zeneli L, Zaltron S, Tiecco G, Pellizzeri S, Focà E, Caruso A, Quiros-Roldan E.   +9 more
europepmc   +2 more sources

Drug resistance mutations in drug-naive HIV type 1 subtype C-infected individuals from rural Malawi. [PDF]

, 2010
In this preliminary study we show that in 2008, 3 years after antiretroviral therapy was introduced into the Karonga District, Malawi, a greater than expected number of drug-naive individuals have been infected with HIV-1 subtype C virus harboring major ...
Grace P. McCormack, Emmanuel Banda, Judith R. Glynn, Bansode, Vijay, McCormack, Grace P., Glynn, Judith R., Neil French, French, Neil, Glynn, Judith R, Zuzanna J. Drebert, Banda, Emmanuel, Drebert, Zuzanna J., Molesworth, Anna, Vijay Bansode, Travers, Simon AA, Amelia Crampin, Drebert, Zuzanna, McCormack, Grace P, Crampin, Amelia, Anna Molesworth, Drebert, Zuzanna J, Simon A.A. Travers, Travers, Simon A A, Travers, Simon A.A., Ngwira, Bagrey, Bagrey Ngwira   +25 more
core   +1 more source

Analysis of prevalence of HIV-1 primary resistance to antiretroviral drugs in the territory of Moscow and Moscow region

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. To analyze the level of HIV drug resistance among primary patients (who did not receive antiretroviral therapy (ART)) living in the Moscow region, where access to the antiretroviral therapy is quite high.Material and methods.
M. N. Nosik, K. A. Ryzhov, A. V. Kravchenko, S. E. Sevostyanihin, U. A. Kuimova, А. B. Potapova, A. L. Sobkin   +6 more
doaj   +1 more source

Prevalence of acquired drug resistance mutations in antiretroviral- experiencing subjects from 2012 to 2017 in Hunan Province of central South China

Virology Journal, 2020
Background There are few data on the prevalence of acquired drug resistance mutations (ADRs) in Hunan Province, China, that could affect the effectiveness of antiretroviral therapy (ART). Objectives The main objectives of this study were to determine the
Xiaobai Zou, Jianmei He, Jun Zheng, Roberta Malmgren, Weisi Li, Xiuqing Wei, Guoqiang Zhang, Xi Chen   +7 more
doaj   +1 more source

"Plasmodium falciparum" Drug Resistance, Molecular Genotyping and Generation of a Malaria Resistance Genogram by DNA Microarray-Based Technology [PDF]

, 2006
Prior to the 2001 malarial treatment policy change in Tanzania, studies were conducted to assess the efficacy of sulfadoxine-pyrimethamine (SP) and usefulness of molecular markers in monitoring SP resistance.
Mugittu, Kefas Nasongelya
core   +1 more source